PDB entry 5mky

View 5mky on RCSB PDB site
Description: BROMODOMAIN OF HUMAN BRD9 WITH 4-chloro-2-methyl-5-((2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)amino)pyridazin-3(2H)-one
Class: transcription
Keywords: brd9, inhibitor, histone, epigenetic reader, bromodomain, transcription
Deposited on 2016-12-05, released 2017-12-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-24, with a file datestamp of 2018-01-19.
Experiment type: XRAY
Resolution: 1.67 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Bromodomain-containing protein 9
  Species: Homo sapiens [TaxId:9606]
  Gene: BRD9, UNQ3040/PRO9856
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9H8M2 (Start-105)
  Domains in SCOPe 2.08: d5mkya_
• Heterogens: I0D, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >5mkyA (A:)
  gaenestpiqqllehflrqlqrkdphgffafpvtdaiapgysmiikhpmdfgtmkdkiva
  neyksvtefkadfklmcdnamtynrpdtvyyklakkilhagfkmms
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >5mkyA (A:)
  stpiqqllehflrqlqrkdphgffafpvtdaiapgysmiikhpmdfgtmkdkivaneyks
  vtefkadfklmcdnamtynrpdtvyyklakkilhagfkmms