PDB entry 5mio

View 5mio on RCSB PDB site
Description: kif2c-darpin fusion protein bound to tubulin
Class: motor protein
Keywords: KINESIN-13 MICROTUBULE ATPASE MOTOR PROTEIN, motor protein
Deposited on 2016-11-28, released 2017-07-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-06, with a file datestamp of 2017-09-01.
Experiment type: XRAY
Resolution: 3.19 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tubulin alpha-1B chain
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5mioa1, d5mioa2
  • Chain 'B':
    Compound: Tubulin beta chain
    Species: Ovis aries [TaxId:9940]
    Database cross-references and differences (RAF-indexed):
    • Uniprot D0VWY9 (0-End)
      • conflict (200)
      • conflict (315)
    Domains in SCOPe 2.07: d5miob1, d5miob2
  • Chain 'C':
    Compound: Kinesin-like protein KIF2C,KIF2C FUSED TO A DARPIN,KIF2C FUSED TO A DARPIN
    Species: Homo sapiens [TaxId:9606]
    Gene: KIF2C, KNSL6
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99661
      • engineered mutation (116)
      • engineered mutation (165)
    • PDB 5MIO (408-426)
    • PDB 5MIO (427-End)
  • Heterogens: GTP, MG, GDP, LOC, ANP

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5mioA (A:)
    mrecisihvgqagvqignacwelyclehgiqpdgqmpsdktigggddsfntffsetgagk
    hvpravfvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvld
    rirkladqctglqgflvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvsta
    vvepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrlisqivssita
    slrfdgalnvdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepan
    qmvkcdprhgkymaccllyrgdvvpkdvnaaiatiktkrsiqfvdwcptgfkvginyqpp
    tvvpggdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefse
    aredmaalekdyeevgvdsvegegeeegeey
    

    Sequence, based on observed residues (ATOM records): (download)
    >5mioA (A:)
    mrecisihvgqagvqignacwelyclehgiqpdgqmpsdsfntffsetgagkhvpravfv
    dleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvldrirkladq
    ctglqgflvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvstavvepynsi
    ltthttlehsdcafmvdneaiydicrrnldierptytnlnrlisqivssitaslrfdgal
    nvdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepanqmvkcdpr
    hgkymaccllyrgdvvpkdvnaaiatiktkrsiqfvdwcptgfkvginyqpptvvpggdl
    akvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefsearedmaal
    ekdyeevgv
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5mioB (B:)
    mreivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneatgnkyv
    prailvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
    rkesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvmpspkvsdtvv
    epynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttcl
    rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqyraltvpeltqqmfdsknmm
    aacdprhgryltvaaifrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprg
    lkmsatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvs
    eyqqyqdatadeqgefeeeegedea
    

    Sequence, based on observed residues (ATOM records): (download)
    >5mioB (B:)
    mreivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneatgnkyv
    prailvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
    rkesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvmpspkvsdtvv
    epynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttcl
    rfpgqlnadlrklavnmvpfprlhffmpgfapltqyraltvpeltqqmfdsknmmaacdp
    rhgryltvaaifrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprglkmsa
    tfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvseyqqy
    qda
    

  • Chain 'C':
    No sequence available.