PDB entry 5m2v

View 5m2v on RCSB PDB site
Description: Structure of GluK1 ligand-binding domain (S1S2) in complex with (2S,4R)-4-(2-carboxyphenoxy)pyrrolidine-2-carboxylic acid at 3.18 A resolution
Class: membrane protein
Keywords: Kainate receptor ligand-binding domain, GluK1-LBD, GluK1-S1S2, antagonist, membrane protein
Deposited on 2016-10-13, released 2017-01-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-08-09, with a file datestamp of 2017-08-04.
Experiment type: XRAY
Resolution: 3.18 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamate receptor ionotropic, kainate 1,Glutamate receptor ionotropic, kainate 1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Grik1, Glur5
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22756 (Start-115)
      • conflict (33)
      • linker (116-117)
    • Uniprot P22756 (118-256)
    Domains in SCOPe 2.08: d5m2va_
  • Chain 'B':
    Compound: Glutamate receptor ionotropic, kainate 1,Glutamate receptor ionotropic, kainate 1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Grik1, Glur5
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22756 (Start-115)
      • conflict (33)
      • linker (116-117)
    • Uniprot P22756 (118-256)
    Domains in SCOPe 2.08: d5m2vb_
  • Heterogens: 7E5, SO4, CL

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5m2vA (A:)
ganrtlivttileepyvmyrksdkplygndrfegycldllkelsnilgflydvklvpdgk
ygaqndkgewngmvkelidhradlavapltityvrekvidfskpfmtlgisilyrkgtpi
dsaddlakqtkieygavrdgstmtffkkskistyekmwafmssrqqsalvknsdegiqrv
lttdyallmestsieyvtqrncnltqigglidskgygvgtpigspyrdkitiailqlqee
gklhmmkekwwrgngcp

    Sequence, based on observed residues (ATOM records): (download) 
    >5m2vA (A:)
tlivttileepyvmyrksdkplygndrfegycldllkelsnilgflydvklvpdgkygaq
ndkgewngmvkelidhradlavapltityvrekvidfskpfmtlgisilyrkgtpidsad
dlakqtkieygavrdgstmtffkkskistyekmwafmssrqqsalvknsdegiqrvlttd
yallmestsieyvtqrncnltqigglidskgygvgtpigspyrdkitiailqlqeegklh
mmkekwwrgcp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5m2vB (B:)
ganrtlivttileepyvmyrksdkplygndrfegycldllkelsnilgflydvklvpdgk
ygaqndkgewngmvkelidhradlavapltityvrekvidfskpfmtlgisilyrkgtpi
dsaddlakqtkieygavrdgstmtffkkskistyekmwafmssrqqsalvknsdegiqrv
lttdyallmestsieyvtqrncnltqigglidskgygvgtpigspyrdkitiailqlqee
gklhmmkekwwrgngcp

    Sequence, based on observed residues (ATOM records): (download) 
    >5m2vB (B:)
tlivttileepyvmyrksdkplygndrfegycldllkelsnilgflydvklvpdgkygaq
ndkgewngmvkelidhradlavapltityvrekvidfskpfmtlgisilyrkgtpidsad
dlakqtkieygavrdgstmtffkkskistyekmwafmssrqqsalvknsdegiqrvlttd
yallmestsieyvtqrncnltqigglidskgygvgtpigspyrdkitiailqlqeegklh
mmkekwwrgngcp