PDB entry 5lyx

View 5lyx on RCSB PDB site
Description: crystal structure of human methionine aminopeptidase-2 in complex; with an inhibitor 5-((r)-1-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl- pyrrolidin-2-ylmethoxy)-isoquinoline
Deposited on 2016-09-29, released 2017-08-16
The last revision was dated 2017-08-16, with a file datestamp of 2017-08-11.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Methionine aminopeptidase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: METAP2, MNPEP, P67EIF2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 7BF, MN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.07, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >5lyxA (A:)
    mgpkvqtdppsvpicdlypngvfpkgqeceypptqdgrtaawrttseekkaldqaseeiw
    ndfreaaeahrqvrkyvmswikpgmtmieicekledcsrklikenglnaglafptgcsln
    ncaahytpnagdttvlqyddickidfgthisgriidcaftvtfnpkydtllkavkdatnt
    gikcagidvrlcdvgeaiqevmesyeveidgktyqvkpirnlnghsigqyrihagktvpi
    vkggeatrmeegevyaietfgstgkgvvhddmecshymknfdvghvpirlprtkhllnvi
    nenfgtlafcrrwldrlgeskylmalknlcdlgivdpypplcdikgsytaqfehtillrp
    tckevvsrgddyhhhhhh
    

    Sequence, based on observed residues (ATOM records):
    >5lyxA (A:)
    kvqtdppsvpicdlypngvfpkgqeceypptqdgrtaawrttskkaldqaseeiwndfre
    aaeahrqvrkyvmswikpgmtmieicekledcsrklikenglnaglafptgcslnncaah
    ytpnagdttvlqyddickidfgthisgriidcaftvtfnpkydtllkavkdatntgikca
    gidvrlcdvgeaiqevmesyeveidgktyqvkpirnlnghsigqyrihagktvpivkgge
    atrmeegevyaietfgstgkgvvhddmecshymknfdvghvpirlprtkhllnvinenfg
    tlafcrrwldrlgeskylmalknlcdlgivdpypplcdikgsytaqfehtillrptckev
    vsr