PDB entry 5ls3

View 5ls3 on RCSB PDB site
Description: Crystal structure of metallo-beta-lactamase SPM-1 with Y58C mutation
Class: hydrolase
Keywords: metallo-beta-lactamase, carbapenemase, hydrolase
Deposited on 2016-08-22, released 2017-03-15
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-03-15, with a file datestamp of 2017-03-10.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: beta-lactamase imp-1
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: spm-1, bla SPM-1, blaSPM-1, CCBH4851_00081, ICEPaeSP_00028
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8G9Q0 (Start-249)
      • engineered mutation (31)
    Domains in SCOPe 2.06: d5ls3a_
  • Chain 'B':
    Compound: beta-lactamase imp-1
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: spm-1, bla SPM-1, blaSPM-1, CCBH4851_00081, ICEPaeSP_00028
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8G9Q0
      • engineered mutation (31)
    Domains in SCOPe 2.06: d5ls3b_
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5ls3A (A:)
gpkssdhvdlpynltatkidsdvfvvtdrdfcssnvlvakmldgtvvivsspfenlgtqt
lmdwvaktmkpkkvvainthfhldgtggneiykkmgaetwssdltkqlrleenkkdrika
aefyknedlkrrilsshpvpadnvfdlkqgkvfsfsnelvevsfpgpahspdnvvvyfpk
kkllfggcmikpkelgylgdanvkawpdsarrlkkfdakivipghgewggpemvnktikv
aekavgemrl

    Sequence, based on observed residues (ATOM records): (download) 
    >5ls3A (A:)
dhvdlpynltatkidsdvfvvtdrdfcssnvlvakmldgtvvivsspfenlgtqtlmdwv
aktmkpkkvvainthfhldgtggneiykkmgaetwssdltkqlrleenkkdfyknedlkr
rilsshpvpadnvfdlkqgkvfsfsnelvevsfpgpahspdnvvvyfpkkkllfggcmik
pkelgylgdanvkawpdsarrlkkfdakivipghgewggpemvnktikvaekavgemrl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5ls3B (B:)
gpkssdhvdlpynltatkidsdvfvvtdrdfcssnvlvakmldgtvvivsspfenlgtqt
lmdwvaktmkpkkvvainthfhldgtggneiykkmgaetwssdltkqlrleenkkdrika
aefyknedlkrrilsshpvpadnvfdlkqgkvfsfsnelvevsfpgpahspdnvvvyfpk
kkllfggcmikpkelgylgdanvkawpdsarrlkkfdakivipghgewggpemvnktikv
aekavgemrl

    Sequence, based on observed residues (ATOM records): (download) 
    >5ls3B (B:)
sdhvdlpynltatkidsdvfvvtdrdfcssnvlvakmldgtvvivsspfenlgtqtlmdw
vaktmkpkkvvainthfhldgtggneiykkmgaetwssdltkqlrleenkkdrikaaefy
knedlkrrilsshpvpadnvfdlkqgkvfsfsnelvevsfpgpahspdnvvvyfpkkkll
fggcmikpkelgylgdanvkawpdsarrlkkfdakivipghgewggpemvnktikvaeka
vgemr