PDB entry 5llv
View 5llv on RCSB PDB site
Description: Crystal structure of DACM F87M/L110M Transthyretin mutant
Class: transport protein
Keywords: Tetramer, Protein aggregation, N-(7-Dimethylamino-4-Methylcoumarin-3-yl))Maleimide, transport protein
Deposited on
2016-07-28, released
2017-06-07
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-12-13, with a file datestamp of
2017-12-08.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
- Uniprot P02766
- engineered mutation (87)
- engineered mutation (110)
Domains in SCOPe 2.08: d5llva_ - Chain 'B':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
- Uniprot P02766
- engineered mutation (87)
- engineered mutation (110)
Domains in SCOPe 2.08: d5llvb_ - Chain 'C':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
- Uniprot P02766
- engineered mutation (87)
- engineered mutation (110)
Domains in SCOPe 2.08: d5llvc_ - Chain 'D':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
- Uniprot P02766
- engineered mutation (87)
- engineered mutation (110)
Domains in SCOPe 2.08: d5llvd_ - Heterogens: CL, ACT, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5llvA (A:)
mgptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhglt
teeefvegiykveidtksywkalgispmhehaevvftandsgprrytiaamlspysystt
avvtnpke
Sequence, based on observed residues (ATOM records): (download)
>5llvA (A:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispmhehaevvftandsgprrytiaamlspysysttavvtnp
- Chain 'B':
Sequence, based on SEQRES records: (download)
>5llvB (B:)
mgptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhglt
teeefvegiykveidtksywkalgispmhehaevvftandsgprrytiaamlspysystt
avvtnpke
Sequence, based on observed residues (ATOM records): (download)
>5llvB (B:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispmhehaevvftandsgprrytiaamlspysysttavvtnp
- Chain 'C':
Sequence, based on SEQRES records: (download)
>5llvC (C:)
mgptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhglt
teeefvegiykveidtksywkalgispmhehaevvftandsgprrytiaamlspysystt
avvtnpke
Sequence, based on observed residues (ATOM records): (download)
>5llvC (C:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispmhehaevvftandsgprrytiaamlspysysttavvtnp
- Chain 'D':
Sequence, based on SEQRES records: (download)
>5llvD (D:)
mgptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhglt
teeefvegiykveidtksywkalgispmhehaevvftandsgprrytiaamlspysystt
avvtnpke
Sequence, based on observed residues (ATOM records): (download)
>5llvD (D:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispmhehaevvftandsgprrytiaamlspysysttavvtnp