PDB entry 5lax
View 5lax on RCSB PDB site
Description: Crystal structure of HLA_DRB1*04:01 in complex with alpha-enolase peptide 26-40
Class: immune system
Keywords: HLA, autoimmune desease, rheumathoid arthritis, MHC class II, immune system
Deposited on
2016-06-15, released
2016-12-07
The last revision prior to the SCOPe 2.08 freeze date was dated
2016-12-07, with a file datestamp of
2016-12-02.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.19
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: hla class II histocompatibility antigen, dr alpha chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA-DRA, HLA-DRA1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5laxa1, d5laxa2, d5laxa3 - Chain 'B':
Compound: HLA class II histocompatibility antigen, DRB1-4 beta chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA-DRB1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5laxb1, d5laxb2, d5laxb3 - Chain 'C':
Compound: hla class II histocompatibility antigen, dr alpha chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA-DRA, HLA-DRA1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5laxc1, d5laxc2 - Chain 'D':
Compound: HLA class II histocompatibility antigen, DRB1-4 beta chain
Species: Homo sapiens [TaxId:9606]
Gene: HLA-DRB1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5laxd1, d5laxd2, d5laxd3 - Chain 'E':
Compound: alpha-enolase peptideTSKGLFRAAVPSGAS
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Chain 'F':
Compound: alpha-enolase peptideTSKGLFRAAVPSGAS
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Heterogens: MLA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5laxA (A:)
ikeehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgal
aniavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvt
wlrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
dssadlvpr
Sequence, based on observed residues (ATOM records): (download)
>5laxA (A:)
keehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgala
niavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtw
lrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwefd
s
- Chain 'B':
Sequence, based on SEQRES records: (download)
>5laxB (B:)
gdtrprfleqvkhechffngtervrfldryfyhqeeyvrfdsdvgeyravtelgrpdaey
wnsqkdlleqkraavdtycrhnygvgesftvqrrvypevtvypaktqplqhhnllvcsvn
gfypgsievrwfrngqeektgvvstgliqngdwtfqtlvmletvprsgevytcqvehpsl
tspltvewrassadlvpr
Sequence, based on observed residues (ATOM records): (download)
>5laxB (B:)
gdtrprfleqvkhechffngtervrfldryfyhqeeyvrfdsdvgeyravtelgrpdaey
wnsqkdlleqkraavdtycrhnygvgesftvqrrvypevtvypaktqplqhhnllvcsvn
gfypgsievrwfrngqeektgvvstgliqngdwtfqtlvmletvprsgevytcqvehpsl
tspltvewrassa
- Chain 'C':
Sequence, based on SEQRES records: (download)
>5laxC (C:)
ikeehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgal
aniavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvt
wlrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
dssadlvpr
Sequence, based on observed residues (ATOM records): (download)
>5laxC (C:)
keehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgala
niavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtw
lrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
- Chain 'D':
Sequence, based on SEQRES records: (download)
>5laxD (D:)
gdtrprfleqvkhechffngtervrfldryfyhqeeyvrfdsdvgeyravtelgrpdaey
wnsqkdlleqkraavdtycrhnygvgesftvqrrvypevtvypaktqplqhhnllvcsvn
gfypgsievrwfrngqeektgvvstgliqngdwtfqtlvmletvprsgevytcqvehpsl
tspltvewrassadlvpr
Sequence, based on observed residues (ATOM records): (download)
>5laxD (D:)
rprfleqvkhechffngtervrfldryfyhqeeyvrfdsdvgeyravtelgrpdaeywns
qkdlleqkraavdtycrhnygvgesftvqrrvypevtvypaktqplqhhnllvcsvngfy
pgsievrwfrngqeektgvvstgliqngdwtfqtlvmletvprsgevytcqvehpsltsp
ltvewras
- Chain 'E':
No sequence available.
- Chain 'F':
No sequence available.