PDB entry 5l8w

View 5l8w on RCSB PDB site
Description: Structure of USP12-UB-PRG/UAF1
Class: structural protein
Keywords: DUB-Activator complex USP1 paralog, STRUCTURAL PROTEIN
Deposited on 2016-06-08, released 2016-09-28
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-11-30, with a file datestamp of 2016-11-25.
Experiment type: XRAY
Resolution: 2.79 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin carboxyl-terminal hydrolase 12
    Species: Homo sapiens [TaxId:9606]
    Gene: USP12, UBH1, USP12L1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5l8wa_
  • Chain 'B':
    Compound: WD repeat-containing protein 48
    Species: Homo sapiens [TaxId:9606]
    Gene: WDR48, KIAA1449, UAF1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8TAF3
      • conflict (368)
  • Chain 'C':
    Compound: Polyubiquitin-B
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5l8wc_
  • Heterogens: AYE, ZN, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5l8wA (A:)
    hhhhhhmeilmtvskfasictmganasalekeigpeqfpvnehyfglvnfgntcycnsvl
    qalyfcrpfrekvlayksqprkkeslltcladlfhsiatqkkkvgvippkkfitrlrken
    elfdnymqqdaheflnyllntiadilqeerkqekqngrlpngnidnennnstpdptwvhe
    ifqgtltnetrcltcetisskdedfldlsvdveqntsithclrgfsntetlcseykyyce
    ecrskqeahkrmkvkklpmilalhlkrfkymdqlhrytklsyrvvfplelrlfntsgdat
    npdrmydlvavvvhcgsgpnrghyiaivkshdfwllfdddivekidaqaieefygltsdi
    sknsesgyilfyqsrd
    

    Sequence, based on observed residues (ATOM records): (download)
    >5l8wA (A:)
    nehyfglvnfgntcycnsvlqalyfcrpfrekvlayksqprkkeslltcladlfhsiatq
    kkkvgvippkkfitrlrkenelfdnymqqdaheflnyllntiadilqeerkqekqpdptw
    vheifqgtltnetrcltcetisskdedfldlsvdveqntsithclrgfsntetlcseyky
    yceecrskqeahkrmkvkklpmilalhlkrfkymdqlhrytklsyrvvfplelrlfntsg
    datnpdrmydlvavvvhcgsgpnrghyiaivkshdfwllfdddivekidaqaieefyglt
    sdisknsesgyilfyqsrd
    

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5l8wC (C:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrg