PDB entry 5l7p

View 5l7p on RCSB PDB site
Description: In silico-powered specific incorporation of photocaged Dopa at multiple protein sites
Class: ligase
Keywords: TyrRS, ligase
Deposited on 2016-06-03, released 2017-09-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-09-27, with a file datestamp of 2017-09-22.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine--tRNA ligase
    Species: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) [TaxId:243232]
    Gene: tyrS, MJ0389
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q57834 (Start-317)
      • engineered mutation (43)
      • engineered mutation (76)
      • engineered mutation (81)
      • engineered mutation (120)
      • engineered mutation (169-170)
      • engineered mutation (173)
      • engineered mutation (178)
      • engineered mutation (191)
      • engineered mutation (297)
    Domains in SCOPe 2.08: d5l7pa_
  • Chain 'B':
    Compound: Tyrosine--tRNA ligase
    Species: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) [TaxId:243232]
    Gene: tyrS, MJ0389
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q57834 (12-317)
      • engineered mutation (43)
      • engineered mutation (76)
      • engineered mutation (81)
      • engineered mutation (120)
      • engineered mutation (169-170)
      • engineered mutation (173)
      • engineered mutation (178)
      • engineered mutation (191)
      • engineered mutation (297)
    Domains in SCOPe 2.08: d5l7pb_
  • Heterogens: 1PE, CA, CL, BUU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5l7pA (A:)
mrgshhhhhhgsmdefemikrntseiiseeelrevlkkdeksaaigfepsgkihlghylq
ikkmidlqnagfdiiiiladlaaylnqkgeldeirkigdynkkvfeamglkakyvygsef
aldkdytlnvyrlalkttlkrarrsmeliaredenpkvaeviypimqvnaahymgvdvnv
ggmeqrkihmlqrellpkkvvcihnpvltgldgegkmssskgnfiavddspeeirakikk
aycpagvvegnpimeiakyfleypltikrpekfggdltvnsyeeleslfknkelhpmrlk
navaeelikilepirkrl

    Sequence, based on observed residues (ATOM records): (download) 
    >5l7pA (A:)
defemikrntseiiseeelrevlkkdeksaaigfepsgkihlghylqikkmidlqnagfd
iiiiladlaaylnqkgeldeirkigdynkkvfeamglkakyvygsefaldkdytlnvyrl
alkttlkrarrsmelianpkvaeviypimqvnaahymgvdvnvggmeqrkihmlqrellp
kkvvcihnpvltgldgegkmssskgnfiavddspeeirakikkaycpagvvegnpimeia
kyfleypltikrpekfggdltvnsyeeleslfknkelhpmrlknavaeelikilepirkr
l

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5l7pB (B:)
mrgshhhhhhgsmdefemikrntseiiseeelrevlkkdeksaaigfepsgkihlghylq
ikkmidlqnagfdiiiiladlaaylnqkgeldeirkigdynkkvfeamglkakyvygsef
aldkdytlnvyrlalkttlkrarrsmeliaredenpkvaeviypimqvnaahymgvdvnv
ggmeqrkihmlqrellpkkvvcihnpvltgldgegkmssskgnfiavddspeeirakikk
aycpagvvegnpimeiakyfleypltikrpekfggdltvnsyeeleslfknkelhpmrlk
navaeelikilepirkrl

    Sequence, based on observed residues (ATOM records): (download) 
    >5l7pB (B:)
mdefemikrntseiiseeelrevlkkdeksaaigfepsgkihlghylqikkmidlqnagf
diiiiladlaaylnqkgeldeirkigdynkkvfeamglkakyvygsefaldkdytlnvyr
lalkttlkrarrsmeliaredenpkvaeviypimqvnaahymgvdvnvggmeqrkihmlq
rellpkkvvcihnpvltgldgegkmssskgnfiavddspeeirakikkaycpagvvegnp
imeiakyfleypltikrpekfggdltvnsyeeleslfknkelhpmrlknavaeelikile
pirkrl