PDB entry 5l6d

View 5l6d on RCSB PDB site
Description: crystal structure of the human mettl3-mettl14 complex bound to sah
Deposited on 2016-05-29, released 2016-10-12
The last revision was dated 2016-10-12, with a file datestamp of 2016-10-07.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: N6-adenosine-methyltransferase 70 kDa subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: METTL3, MTA70
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: N6-adenosine-methyltransferase subunit METTL14
    Species: Homo sapiens [TaxId:9606]
    Gene: METTL14, KIAA1627
    Database cross-references and differences (RAF-indexed):
  • Heterogens: SAH, MG, ACT, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.07, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >5l6dA (A:)
    altqsvggdssadrlfppqwiccdiryldvsilgkfavvmadppwdihmelpygtltdde
    mrrlnipvlqddgflflwvtgramelgreclnlwgyervdeiiwvktnqlqriirtgrtg
    hwlnhgkehclvgvkgnpqgfnqgldcdvivaevrstshkpdeiygmierlspgtrkiel
    fgrphnvqpnwitlgnqldgihlldpdvvarfkqrypdgiiskpknl
    

    Sequence, based on observed residues (ATOM records):
    >5l6dA (A:)
    lfppqwiccdiryldvsilgkfavvmadppwdipygtltddemrrlnipvlqddgflflw
    vtgramelgreclnlwgyervdeiiwvktnqlqriihwlnhgkehclvgvkgnpqgfnqg
    ldcdvivaevrstshkpdeiygmierlspgtrkielfgrphnvqpnwitlgnqldgihll
    dpdvvarfkqrypdgiisk
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >5l6dB (B:)
    lkgtqslnphndycqhfvdtghrpqnfirdvgladrfeeypklrelirlkdeliaksntp
    pmylqadieafdireltpkfdvilleppleeyyretgitanekcwtwddimkleideiaa
    prsfiflwcgsgegldlgrvclrkwgyrrcedicwiktnknnpgktktldpkavfqrtke
    hclmgikgtvkrstdgdfihanvdidliiteepeigniekpveifhiiehfclgrrrlhl
    fgrdstirpgwltvgptltnsnynaetyasyfsapnsyltgcteeierl
    

    Sequence, based on observed residues (ATOM records):
    >5l6dB (B:)
    ndycqhfvdtghrpqnfirdirlkdeliaksntppmylqadieafdireltpkfdville
    ppleeyyrkcwtwddimkleideiaaprsfiflwcgsgegldlgrvclrkwgyrrcedic
    wiktnknnpgldpkavfqrtkehclmgikgtvdidliiteepeigniekpveifhiiehf
    clgrrrlhlfgrdstirpgwltvgptltnsnynaetyasyfsapnsyltgcteeierl