PDB entry 5l42

View 5l42 on RCSB PDB site
Description: Leishmania major Pteridine reductase 1 (PTR1) in complex with compound 3
Class: oxidoreductase
Keywords: Leishmania major, Pteridine reductase 1, PTR1, Oxidoreductase
Deposited on 2016-05-24, released 2017-05-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-27, with a file datestamp of 2017-09-22.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pteridine reductase 1
    Species: Leishmania major [TaxId:5664]
    Gene: PTR1, HMTXR, L1063.01, LmjF23.0270, LmjF_23_0270
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q01782 (Start-287)
      • engineered mutation (161)
    Domains in SCOPe 2.07: d5l42a_
  • Chain 'B':
    Compound: pteridine reductase 1
    Species: Leishmania major [TaxId:5664]
    Gene: PTR1, HMTXR, L1063.01, LmjF23.0270, LmjF_23_0270
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q01782 (Start-287)
      • engineered mutation (161)
    Domains in SCOPe 2.07: d5l42b_
  • Chain 'C':
    Compound: pteridine reductase 1
    Species: Leishmania major [TaxId:5664]
    Gene: PTR1, HMTXR, L1063.01, LmjF23.0270, LmjF_23_0270
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q01782 (Start-287)
      • engineered mutation (161)
    Domains in SCOPe 2.07: d5l42c_
  • Chain 'D':
    Compound: pteridine reductase 1
    Species: Leishmania major [TaxId:5664]
    Gene: PTR1, HMTXR, L1063.01, LmjF23.0270, LmjF_23_0270
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q01782 (Start-287)
      • engineered mutation (161)
    Domains in SCOPe 2.07: d5l42d_
  • Heterogens: 6J6, NDP, GOL, ACT, PGE, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5l42A (A:)
mtaptvpvalvtgaakrlgrsiaeglhaegyavclhyhrsaaeanalsatlnarrpnsai
tvqadlsnvatapvsgadgsapvtlftrcaelvaacythwgrcdvlvnnassfyptpllr
ndedghepcvgdreametatadlfgsnaiapyflikafahrvagtpakhrgtnysiinmv
damtnqpllgytiytmakgalegltrsaalelaplqirvngvgpglsvlvddmppavweg
hrskvplyqrdssaaevsdvviflcsskakyitgtcvkvdggysltra

    Sequence, based on observed residues (ATOM records): (download) 
    >5l42A (A:)
tvpvalvtgaakrlgrsiaeglhaegyavclhyhrsaaeanalsatlnarrpnsaitvqa
dlsnvatapapvtlftrcaelvaacythwgrcdvlvnnassfyptpllrreametatadl
fgsnaiapyflikafahrvagtpakhrgtnysiinmvdamtnqpllgytiytmakgaleg
ltrsaalelaplqirvngvgpglsvlvddmppavweghrskvplyqrdssaaevsdvvif
lcsskakyitgtcvkvdggysltra

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5l42B (B:)
mtaptvpvalvtgaakrlgrsiaeglhaegyavclhyhrsaaeanalsatlnarrpnsai
tvqadlsnvatapvsgadgsapvtlftrcaelvaacythwgrcdvlvnnassfyptpllr
ndedghepcvgdreametatadlfgsnaiapyflikafahrvagtpakhrgtnysiinmv
damtnqpllgytiytmakgalegltrsaalelaplqirvngvgpglsvlvddmppavweg
hrskvplyqrdssaaevsdvviflcsskakyitgtcvkvdggysltra

    Sequence, based on observed residues (ATOM records): (download) 
    >5l42B (B:)
tvpvalvtgaakrlgrsiaeglhaegyavclhyhrsaaeanalsatlnarrpnsaitvqa
dlsnvatapapvtlftrcaelvaacythwgrcdvlvnnassfyptpllrdreametatad
lfgsnaiapyflikafahrvagtpakhrgtnysiinmvdamtnqpllgytiytmakgale
gltrsaalelaplqirvngvgpglsvlvddmppavweghrskvplyqrdssaaevsdvvi
flcsskakyitgtcvkvdggysltra

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5l42C (C:)
mtaptvpvalvtgaakrlgrsiaeglhaegyavclhyhrsaaeanalsatlnarrpnsai
tvqadlsnvatapvsgadgsapvtlftrcaelvaacythwgrcdvlvnnassfyptpllr
ndedghepcvgdreametatadlfgsnaiapyflikafahrvagtpakhrgtnysiinmv
damtnqpllgytiytmakgalegltrsaalelaplqirvngvgpglsvlvddmppavweg
hrskvplyqrdssaaevsdvviflcsskakyitgtcvkvdggysltra

    Sequence, based on observed residues (ATOM records): (download) 
    >5l42C (C:)
tvpvalvtgaakrlgrsiaeglhaegyavclhyhrsaaeanalsatlnarrpnsaitvqa
dlsnvatapsapvtlftrcaelvaacythwgrcdvlvnnassfyptpllrreametatad
lfgsnaiapyflikafahrvagtpakhrgtnysiinmvdamtnqpllgytiytmakgale
gltrsaalelaplqirvngvgpglsvlvghrskvplyqrdssaaevsdvviflcsskaky
itgtcvkvdggysltra

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5l42D (D:)
mtaptvpvalvtgaakrlgrsiaeglhaegyavclhyhrsaaeanalsatlnarrpnsai
tvqadlsnvatapvsgadgsapvtlftrcaelvaacythwgrcdvlvnnassfyptpllr
ndedghepcvgdreametatadlfgsnaiapyflikafahrvagtpakhrgtnysiinmv
damtnqpllgytiytmakgalegltrsaalelaplqirvngvgpglsvlvddmppavweg
hrskvplyqrdssaaevsdvviflcsskakyitgtcvkvdggysltra

    Sequence, based on observed residues (ATOM records): (download) 
    >5l42D (D:)
tvpvalvtgaakrlgrsiaeglhaegyavclhyhrsaaeanalsatlnarrpnsaitvqa
dlsnvatapapvtlftrcaelvaacythwgrcdvlvnnassfyptpllrametatadlfg
snaiapyflikafahrvagtpakhrgtnysiinmvdamtnqpllgytiytmakgaleglt
rsaalelaplqirvngvgpglsvlvghrskvplyqrdssaaevsdvviflcsskakyitg
tcvkvdggysltra