SCOPe 2.07: Structural Classification of Proteins

PDB entry 5l2o

View 5l2o on RCSB PDB site
Description: Crystal Structure of ALDH1A1 in complex with BUC22
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: ALDH1A1 Inhibitor, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Deposited on 2016-08-02, released 2017-03-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-20, with a file datestamp of 2017-09-15.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Retinal dehydrogenase 1
Species: Homo sapiens [TaxId:9606]
Gene: ALDH1A1, ALDC, ALDH1, PUMB1
Database cross-references and differences (RAF-indexed):
- Uniprot P00352 (Start-500)
Domains in SCOPe 2.07: d5l2oa_
Chain 'B':
Compound: Retinal dehydrogenase 1
Species: Homo sapiens [TaxId:9606]
Gene: ALDH1A1, ALDC, ALDH1, PUMB1
Database cross-references and differences (RAF-indexed):
- Uniprot P00352 (Start-500)
Domains in SCOPe 2.07: d5l2ob_
Chain 'C':
Compound: Retinal dehydrogenase 1
Species: Homo sapiens [TaxId:9606]
Gene: ALDH1A1, ALDC, ALDH1, PUMB1
Database cross-references and differences (RAF-indexed):
- Uniprot P00352 (Start-500)
Domains in SCOPe 2.07: d5l2oc_
Chain 'D':
Compound: Retinal dehydrogenase 1
Species: Homo sapiens [TaxId:9606]
Gene: ALDH1A1, ALDC, ALDH1, PUMB1
Database cross-references and differences (RAF-indexed):
- Uniprot P00352 (Start-500)
Domains in SCOPe 2.07: d5l2od_
Chain 'E':
Compound: Retinal dehydrogenase 1
Species: Homo sapiens [TaxId:9606]
Gene: ALDH1A1, ALDC, ALDH1, PUMB1
Database cross-references and differences (RAF-indexed):
- Uniprot P00352 (Start-500)
Domains in SCOPe 2.07: d5l2oe_
Chain 'F':
Compound: Retinal dehydrogenase 1
Species: Homo sapiens [TaxId:9606]
Gene: ALDH1A1, ALDC, ALDH1, PUMB1
Database cross-references and differences (RAF-indexed):
- Uniprot P00352 (Start-500)
Domains in SCOPe 2.07: d5l2of_
Chain 'G':
Compound: Retinal dehydrogenase 1
Species: Homo sapiens [TaxId:9606]
Gene: ALDH1A1, ALDC, ALDH1, PUMB1
Database cross-references and differences (RAF-indexed):
- Uniprot P00352 (Start-500)
Domains in SCOPe 2.07: d5l2og_
Chain 'H':
Compound: Retinal dehydrogenase 1
Species: Homo sapiens [TaxId:9606]
Gene: ALDH1A1, ALDC, ALDH1, PUMB1
Database cross-references and differences (RAF-indexed):
- Uniprot P00352 (Start-500)
Domains in SCOPe 2.07: d5l2oh_
Heterogens: 6ZW, YB, CL, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>5l2oA (A:)
msssgtpdlpvlltdlkiqytkifinnewhdsvsgkkfpvfnpateeelcqveegdkedv
dkavkaarqafqigspwrtmdasergrllykladlierdrlllatmesmnggklysnayl
ndlagciktlrycagwadkiqgrtipidgnfftytrhepigvcgqiipwnfplvmliwki
gpalscgntvvvkpaeqtpltalhvaslikeagfppgvvnivpgygptagaaisshmdid
kvaftgstevgklikeaagksnlkrvtlelggkspcivladadldnavefahhgvfyhqg
qcciaasrifveesiydefvrrsverakkyilgnpltpgvtqgpqidkeqydkildlies
gkkegaklecgggpwgnkgyfvqptvfsnvtdemriakeeifgpvqqimkfkslddvikr
anntfyglsagvftkdidkaitissalqagtvwvncygvvsaqcpfggfkmsgngrelge
ygfheytevktvtvkisqkns