PDB entry 5l2k

View 5l2k on RCSB PDB site
Description: crystal structure of gem42 tcr-cd1b-gmm complex
Deposited on 2016-08-02, released 2016-11-16
The last revision was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: T-cell surface glycoprotein cd1b
    Species: Homo sapiens [TaxId:9606]
    Gene: CD1B
    Database cross-references and differences (RAF-indexed):
    • Uniprot P29016 (Start-276)
      • engineered mutation (158)
      • expression tag (277)
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: GEM42 TCR alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5L2K (0-End)
  • Chain 'E':
    Compound: GEM42 TCR beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5L2K (Start-242)
  • Heterogens: NAG, SO4, CL, NA, 6UL, CS, 70E, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.07, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >5l2kA (A:)
    hafqgptsfhviqtssftnstwaqtqgsgwlddlqihgwdsdsgtaiflkpwskgnfsdk
    evaeleeifrvyifgfarevqdfagdfqmkypfeiqgiagcelhsggaivsflrgalggl
    dflsvknascvpspeggsraqkfcaliiqyqgimetvrallyetcpryllgvlnagkadl
    qrqvkpeawlssgpspgpgrlqlvchvsgfypkpvwvmwmrgeqeqqgtqlgdilpnanw
    twylratldvadgeaaglscrvkhsslegqdiilywrgsglndifeaqkiewhehhhhhh
    

    Sequence, based on observed residues (ATOM records):
    >5l2kA (A:)
    fqgptsfhviqtssftnstwaqtqgsgwlddlqihgwdsdsgtaiflkpwskgnfsdkev
    aeleeifrvyifgfarevqdfagdfqmkypfeiqgiagcelhsggaivsflrgalggldf
    lsvknascvpspeggsraqkfcaliiqyqgimetvrallyetcpryllgvlnagkadlqr
    qvkpeawlssgpspgpgrlqlvchvsgfypkpvwvmwmrgeqeqqgtqlgdilpnanwtw
    ylratldvadgeaaglscrvkhsslegqdiilywrg
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >5l2kB (B:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrd
    

  • Chain 'D':
    Sequence, based on SEQRES records:
    >5l2kD (D:)
    gqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrf
    ssflsrskgysylllkelqmkdsasylcavrntggfktifgagtrlfvkaniqnpdpavy
    qlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksd
    facanafnnsiipedtffpspess
    

    Sequence, based on observed residues (ATOM records):
    >5l2kD (D:)
    gqnidqptemtategaivqinctyqtsgfnglfwyqqhageaptflsynvldgleekgrf
    ssflsrskgysylllkelqmkdsasylcavrntggfktifgagtrlfvkaniqnpdpavy
    qlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksd
    facan
    

  • Chain 'E':
    Sequence, based on SEQRES records:
    >5l2kE (E:)
    nagvtqtpkfrvlktgqsmtllcaqdmnheymywyrqdpgmglrlihysvgegttakgev
    pdgynvsrlkkqnfllglesaapsqtsvyfcassprlagdeqffgpgtrltvledlknvf
    ppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqp
    alndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawg
    rad
    

    Sequence, based on observed residues (ATOM records):
    >5l2kE (E:)
    agvtqtpkfrvlktgqsmtllcaqdmnheymywyrqdpgmglrlihysvgegttakgevp
    dgynvsrlkkqnfllglesaapsqtsvyfcassprlagdeqffgpgtrltvledlknvfp
    pevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpa
    lndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgr
    ad