PDB entry 5l0a

View 5l0a on RCSB PDB site
Description: Human muscle fructose-1,6-bisphosphatase E69Q mutant in active R-state in complex with fructose-1,6-bisphosphate
Class: hydrolase
Keywords: Hydrolase, carbohydrate metabolism, glyconeogenesis, muscle izoenzyme, FBPase, R-state, Leucine lock, E69Q, fructose-1, 6-bisphosphate
Deposited on 2016-07-27, released 2017-08-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fructose-1,6-bisphosphatase isozyme 2
    Species: Homo sapiens [TaxId:9606]
    Gene: FBP2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5l0aa_
  • Heterogens: FBP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5l0aA (A:)
tdrspfetdmltltryvmekgrqakgtgeltqllnsmltaikaissavrkaglahlygia
gsvnvtgdqvkkldvlsnslvinmlqssystcvlvseenkdaiitakekrgkyvvcfdpl
dgssnidclasigtifaiyrktsedepsekdalqcgrnivaagyalygsatlvalstgqg
vdlfmldpalgefvlvekdvkikkkgkiyslnegyakyfdaatteyvqkkkfpedgsapy
garyvgsmvadvhrtlvyggiflypanqkspkgklrllyecnpvayiieqagglattgtq
pvldvkpeaihqrvplilgspedvqeyltcvqknqags

    Sequence, based on observed residues (ATOM records): (download) 
    >5l0aA (A:)
dmltltryeltqllnsmltaikaissavrkkkldvlsnslvinmlqssystcvlvseenk
daiitakekrgkyvvcfdpldasigtifaiyekdalqcgrnivaagyalygsatlvalst
gqgvdlfmldpalgefvlvekdvkikkkgkiyslnegyakyfdaatteyvqkkkfpedgs
apygaryvgsmvadvhrtlvyggiflypanqkspkgklrllyecnpvayiieqagglatt
gtqpvldvkpeaihqrvplilgspedvqeyltcvqkn