PDB entry 5kyf

View 5kyf on RCSB PDB site
Description: Crystal structure of USP7 catalytic domain [L299A] mutant in complex with ubiquitin
Class: hydrolase
Keywords: USP7 catalytic domain, deubiquitinase, L299A mutant, ubiquitin, HYDROLASE
Deposited on 2016-07-21, released 2017-08-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-02-20, with a file datestamp of 2019-02-15.
Experiment type: XRAY
Resolution: 1.45 Å
R-factor: N/A
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'B':
    Compound: Ubiquitin carboxyl-terminal hydrolase 7
    Species: Homo sapiens [TaxId:9606]
    Gene: USP7, HAUSP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q93009 (4-End)
      • engineered mutation (95)
    Domains in SCOPe 2.08: d5kyfb_
  • Chain 'C':
    Compound: Polyubiquitin-B
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5kyfc_
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5kyfB (B:)
gshmkkhtgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrv
fyelqhsdkpvgtkkltksfgwetldsfmqhdvqeacrvlldnvenkmkgtcvegtipkl
frgkmvsyiqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydage
hglqeaekgvkfltlppvlhlqlmrfmydpqtdqnikindrfefpeqlpldeflqktdpk
dpanyilhavlvhsgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghdd
dlsvrhctnaymlvyiresklsevlqavtdhdipqqlverlqeekrieaqk

    Sequence, based on observed residues (ATOM records): (download) 
    >5kyfB (B:)
kkhtgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrvfyel
qhsdkpvgtkkltksfgwetldsfmqhdvqeacrvlldnvenkmkgtcvegtipklfrgk
mvsyiqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydagehglq
eaekgvkfltlppvlhlqlmrfmydpqtdqnikindrfefpeqlpldeflqktdpkdpan
yilhavlvhsgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghdvrhct
naymlvyiresklsevlqavtdhdipqqlverlqeekrie

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5kyfC (C:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrgg