PDB entry 5kyb

View 5kyb on RCSB PDB site
Description: Crystal structure of the apo-form of USP7 catalytic domain [V302K] mutant
Class: hydrolase
Keywords: USP7 catalytic domain, deubiquitinase, V302K mutant, HYDROLASE
Deposited on 2016-07-21, released 2017-08-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-02-20, with a file datestamp of 2019-02-15.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin carboxyl-terminal hydrolase 7
    Species: Homo sapiens [TaxId:9606]
    Gene: USP7, HAUSP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q93009
      • engineered mutation (98)
    Domains in SCOPe 2.08: d5kyba_
  • Chain 'B':
    Compound: Ubiquitin carboxyl-terminal hydrolase 7
    Species: Homo sapiens [TaxId:9606]
    Gene: USP7, HAUSP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q93009
      • engineered mutation (98)
    Domains in SCOPe 2.08: d5kybb_
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5kybA (A:)
gshmkkhtgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrv
fyelqhsdkpvgtkkltksfgwetldsfmqhdvqelcrklldnvenkmkgtcvegtipkl
frgkmvsyiqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydage
hglqeaekgvkfltlppvlhlqlmrfmydpqtdqnikindrfefpeqlpldeflqktdpk
dpanyilhavlvhsgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghdd
dlsvrhctnaymlvyiresklsevlqavtdhdipqqlverlqeekrieaqk

    Sequence, based on observed residues (ATOM records): (download) 
    >5kybA (A:)
tgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrvfyelqhs
dkpvgtkkltksfgwetldsfmqhdvqelcrklldnvenkmkgtcvegtipklfrgkmvs
yiqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydagehglqeae
kgvkfltlppvlhlqlmrfmynikindrfefpeqlpldeflqktdpkdpanyilhavlvh
sgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghhctnaymlvyiresk
lsevlqavtdhdipqqlverlqeekrieaq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5kybB (B:)
gshmkkhtgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrv
fyelqhsdkpvgtkkltksfgwetldsfmqhdvqelcrklldnvenkmkgtcvegtipkl
frgkmvsyiqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydage
hglqeaekgvkfltlppvlhlqlmrfmydpqtdqnikindrfefpeqlpldeflqktdpk
dpanyilhavlvhsgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghdd
dlsvrhctnaymlvyiresklsevlqavtdhdipqqlverlqeekrieaqk

    Sequence, based on observed residues (ATOM records): (download) 
    >5kybB (B:)
khtgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrvfyelq
hsdkpvgtkkltksfgwetldsfmqhdvqelcrklldnvenkmkgtcvegtipklfrgkm
vsyiqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydagehglqe
aekgvkfltlppvlhlqlmrfmynikindrfefpeqlpldeflqktdpkdpanyilhavl
vhsgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghhctnaymlvyire
sklsevlqavtdhdipqqlverlqeekrieaq