PDB entry 5knu

View 5knu on RCSB PDB site
Description: Crystal structure of E. coli hypoxanthine phosphoribosyltransferase in complexed with 9-[N,N-(Bis-3-phosphonopropyl)aminomethyl]-9-deazahypoxanthine
Class: transferase/inhibitor
Keywords: Acyclic nucleoside phosphonate, EcHPRT, phosphoribosyltransferase, TRANSFERASE-INHIBITOR complex
Deposited on 2016-06-28, released 2017-07-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-07-19, with a file datestamp of 2017-07-14.
Experiment type: XRAY
Resolution: 2.81 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hypoxanthine-guanine phosphoribosyltransferase
    Species: Escherichia coli [TaxId:562]
    Gene: hpt, ACN002_0124
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5knua_
  • Chain 'B':
    Compound: hypoxanthine-guanine phosphoribosyltransferase
    Species: Escherichia coli [TaxId:562]
    Gene: hpt, ACN002_0124
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5knub_
  • Heterogens: 6WA, MG, EPE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5knuA (A:)
mvrdmkhtvevmipeaeikariaelgrqiterykdsgsdmvlvgllrgsfmfmadlcrev
qvshevdfmtassygsgmsttrdvkilkdldedirgkdvlivediidsgntlskvreils
lrepkslaictlldkpsrrevnvpvefigfsipdefvvgygidyaqryrhlpyigkvill
de

    Sequence, based on observed residues (ATOM records): (download) 
    >5knuA (A:)
rdmkhtvevmipeaeikariaelgrqiterykdsgsdmvlvgllrgsfmfmadlcrevqv
shevdfmtasstrdvkilkdldedirgkdvlivediidsgntlskvreilslrepkslai
ctlldkpsrrevnvpvefigfsipdefvvgygidyaqryrhlpyigkvilld

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5knuB (B:)
mvrdmkhtvevmipeaeikariaelgrqiterykdsgsdmvlvgllrgsfmfmadlcrev
qvshevdfmtassygsgmsttrdvkilkdldedirgkdvlivediidsgntlskvreils
lrepkslaictlldkpsrrevnvpvefigfsipdefvvgygidyaqryrhlpyigkvill
de

    Sequence, based on observed residues (ATOM records): (download) 
    >5knuB (B:)
rdmkhtvevmipeaeikariaelgrqiterykdsgsdmvlvgllrgsfmfmadlcrevqv
shevdfmtassyttrdvkilkdldedirgkdvlivediidsgntlskvreilslrepksl
aictlldkpsrrevnvpvefigfsipdefvvgygidyaqryrhlpyigkvill