PDB entry 5k3y

View 5k3y on RCSB PDB site
Description: Crystal structure of AuroraB/INCENP in complex with BI 811283
Class: transferase
Keywords: Kinase, Inhibitor, transferase
Deposited on 2016-05-20, released 2016-08-17
The last revision prior to the SCOPe 2.06 freeze date was dated 2016-08-17, with a file datestamp of 2016-08-12.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: aurora kinase b-a
    Species: Xenopus laevis [TaxId:8355]
    Gene: aurkb-a, airk2-a
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6DE08
      • conflict (19)
    Domains in SCOPe 2.06: d5k3ya_
  • Chain 'B':
    Compound: aurora kinase b-a
    Species: Xenopus laevis [TaxId:8355]
    Gene: aurkb-a, airk2-a
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6DE08 (Start-279)
      • conflict (19)
    Domains in SCOPe 2.06: d5k3yb_
  • Chain 'C':
    Compound: inner centromere protein a
    Species: Xenopus laevis [TaxId:8355]
    Gene: incenp-a
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: inner centromere protein a
    Species: Xenopus laevis [TaxId:8355]
    Gene: incenp-a
    Database cross-references and differences (RAF-indexed):
  • Heterogens: TPO, 6Q4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5k3yA (A:)
gtalaempkrkftiddfdivrplgkgkfgnvylarekqnkfimalkvlfksqlekegveh
qlrreieiqshlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsatf
meeladalhycherkvihrdikpenllmgykgelkiadfgwsvhapslrrrtmcgtldyl
ppemiegkthdekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdgs
kdliskllryhppqrlplkgvmehpwvkansrrvlppvyq

    Sequence, based on observed residues (ATOM records): (download) 
    >5k3yA (A:)
ftiddfdivrplgkgkfgnvylarekqnkfimalkvlfksqlekegvehqlrreieiqsh
lrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsatfmeeladalhyc
herkvihrdikpenllmgykgelkiadfgwsvhapslrrrmcgtldylppemiegkthde
kvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdgskdliskllryhp
pqrlplkgvmehpwvkansrrvlppvy

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5k3yB (B:)
gtalaempkrkftiddfdivrplgkgkfgnvylarekqnkfimalkvlfksqlekegveh
qlrreieiqshlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsatf
meeladalhycherkvihrdikpenllmgykgelkiadfgwsvhapslrrrtmcgtldyl
ppemiegkthdekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdgs
kdliskllryhppqrlplkgvmehpwvkansrrvlppvyq

    Sequence, based on observed residues (ATOM records): (download) 
    >5k3yB (B:)
alaempkrkftiddfdivrplgkgkfgnvylarekqnkfimalkvlfksqlekegvehql
rreieiqshlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsatfme
eladalhycherkvihrdikpenllmgykgelkiadfgwsvhapslrrrmcgtldylppe
miegkthdekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdgskdl
iskllryhppqrlplkgvmehpwvkansrrvlppvyq

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.