PDB entry 5k25

View 5k25 on RCSB PDB site
Description: Crystal structure of human phosphatase PRL-2 in complex with the ADP-bound Bateman domain of human magnesium transporter CNNM3
Class: hydrolase/transporter protein/protein binding
Keywords: Complex, phosphatase, magnesium transporter, protein binding, HYDROLASE, HYDROLASE-TRANSPORTER PROTEIN-PROTEIN BINDING complex
Deposited on 2016-05-18, released 2016-10-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-10-12, with a file datestamp of 2016-10-07.
Experiment type: XRAY
Resolution: 3.05 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein tyrosine phosphatase type IVA 2
    Species: Homo sapiens [TaxId:9606]
    Gene: PTP4A2, PRL2, PTPCAAX2, BM-008
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q12974 (23-End)
      • expression tag (21-22)
    Domains in SCOPe 2.07: d5k25a1, d5k25a2
  • Chain 'C':
    Compound: Metal transporter CNNM3
    Species: Homo sapiens [TaxId:9606]
    Gene: CNNM3, ACDP3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8NE01 (12-End)
      • expression tag (0-11)
  • Heterogens: ADP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5k25A (A:)
    msyyhhhhhhlestslykkagfamnrpapveisyenmrflithnptnatlnkfteelkky
    gvttlvrvcdatydkapvekegihvldwpfddgapppnqivddwlnllktkfreepgccv
    avhcvaglgrapvlvalaliecgmkyedavqfirqkrrgafnskqllylekyrpkmrlrf
    rdtnghccvq
    

    Sequence, based on observed residues (ATOM records): (download)
    >5k25A (A:)
    famnrpapveisyenmrflithnptnatlnkfteelkkygvttlvrvcdatydkapveke
    gihvldwpfddgapppnqivddwlnllktkfreepgccvavhcvaglgrapvlvalalie
    cgmkyedavqfirqkrrgafnskqllylekyrpkmrl
    

  • Chain 'C':
    No sequence available.