PDB entry 5jzs

View 5jzs on RCSB PDB site
Description: HsaD bound to 3,5-dichloro-4-hydroxybenzoic acid
Class: hydrolase
Keywords: HsaD, inhibitor, M. tuberculosis, cholesterol, infection, hydrolase
Deposited on 2016-05-17, released 2017-04-05
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-04-05, with a file datestamp of 2017-03-31.
Experiment type: XRAY
Resolution: 2.27 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase bphd
  Species: Mycobacterium tuberculosis [TaxId:1773]
  Gene: bphD, AFL40_3716, BN1213_03918, BN1303_03049, ERS007661_00365, ERS007663_01172, ERS007665_00879, ERS007670_01859, ERS007679_00575, ERS007722_01141, ERS007741_03068, ERS013471_01596, ERS024213_01658, ERS027646_02381, ERS027654_01339, ERS027656_01041, ERS027661_00436, ERS124361_01169
  Database cross-references and differences (RAF-indexed):
  • Uniprot A0A045KDP6 (0-283)
  Domains in SCOPe 2.06: d5jzsa_
• Chain 'B':
  Compound: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase bphd
  Species: Mycobacterium tuberculosis [TaxId:1773]
  Gene: bphD, AFL40_3716, BN1213_03918, BN1303_03049, ERS007661_00365, ERS007663_01172, ERS007665_00879, ERS007670_01859, ERS007679_00575, ERS007722_01141, ERS007741_03068, ERS013471_01596, ERS024213_01658, ERS027646_02381, ERS027654_01339, ERS027656_01041, ERS027661_00436, ERS124361_01169
  Database cross-references and differences (RAF-indexed):
  • Uniprot A0A045KDP6 (0-283)
  Domains in SCOPe 2.06: d5jzsb_
• Heterogens: FGZ, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >5jzsA (A:)
  ltfestsrfaevdvdgplklhyheagvgndqtvvllhgggpgaaswtnfsrniavlarhf
  hvlavdqpgyghsdkraehgqfnryaamalkglfdqlglgrvplvgnslgggtavrfald
  yparagrlvlmgpgglsinlfapdptegvkrlskfsvaptrenleaflrvmvydknlitp
  elvdqrfalastpesltatramgksfagadfeagmmwrevyrlrqpvlliwgredrvnpl
  dgalvalktipraqlhvfgqcghwvqvekfdefnkltieflggg
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >5jzsB (B:)
  ltfestsrfaevdvdgplklhyheagvgndqtvvllhgggpgaaswtnfsrniavlarhf
  hvlavdqpgyghsdkraehgqfnryaamalkglfdqlglgrvplvgnslgggtavrfald
  yparagrlvlmgpgglsinlfapdptegvkrlskfsvaptrenleaflrvmvydknlitp
  elvdqrfalastpesltatramgksfagadfeagmmwrevyrlrqpvlliwgredrvnpl
  dgalvalktipraqlhvfgqcghwvqvekfdefnkltieflggg