PDB entry 5jq8

View 5jq8 on RCSB PDB site
Description: Crystal structure of CDK2 in complex with inhibitor ICEC0943
Class: transferase/transferase inhibitor
Keywords: Kinase inhibitor, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2016-05-04, released 2017-02-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-03-15, with a file datestamp of 2017-03-10.
Experiment type: XRAY
Resolution: 1.94 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cyclin-dependent kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2, CDKN2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5jq8a_
  • Heterogens: I73, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5jq8A (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

    Sequence, based on observed residues (ATOM records): (download) 
    >5jq8A (A:)
nfqkvekigegtygvvykarnkltgevvalkkipstaireisllkelnhpnivklldvih
tenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlkpq
nllintegaikladfglarafevvtlwyrapeillgckyystavdiwslgcifaemvtrr
alfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgr
sllsqmlhydpnkrisakaalahpffqdvtkpvphlrl