PDB entry 5jnc

View 5jnc on RCSB PDB site
Description: Crystal structure for the complex of human carbonic anhydrase IV and 4-aminomethylbenzene sulfonamide
Class: lyase/lyase inhibitor
Keywords: Carbonic anhydrase, Lyase, Inhibitor binding, lyase-lyase inhibitor complex
Deposited on 2016-04-29, released 2017-05-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-02-06, with a file datestamp of 2019-02-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carbonic anhydrase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: CA4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5jnca_
  • Chain 'B':
    Compound: Carbonic anhydrase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: CA4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5jncb_
  • Chain 'C':
    Compound: Carbonic anhydrase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: CA4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5jncc_
  • Chain 'D':
    Compound: Carbonic anhydrase 4
    Species: Homo sapiens [TaxId:9606]
    Gene: CA4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5jncd_
  • Heterogens: ZN, 6LH, SO4, ACT, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5jncA (A:)
aeshwcyevqaessnypclvpvkwggncqkdrqspinivttkakvdkklgrfffsgydkk
qtwtvqnnghsvmmllenkasisggglpapyqakqlhlhwsdlpykgsehsldgehfame
mhivhekekgtsrnvkeaqdpedeiavlaflveagtqvnegfqplvealsnipkpemstt
maesslldllpkeeklrhyfrylgslttptcdekvvwtvfrepiqlhreqilafsqklyy
dkeqtvsmkdnvrplqqlgqrtviks

    Sequence, based on observed residues (ATOM records): (download) 
    >5jncA (A:)
aeshwcyevqaessnypclvpvkwggncqkdrqspinivttkakvdkklgrfffsgydkk
qtwtvqnnghsvmmllenkasisggglpapyqakqlhlhwsdlpykgsehsldgehfame
mhivhekekgtsdpedeiavlaflveagtqvnegfqplvealsnipkpemsttmaessll
dllpkeeklrhyfrylgslttptcdekvvwtvfrepiqlhreqilafsqklyydkeqtvs
mkdnvrplqqlgqrtviks

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5jncB (B:)
aeshwcyevqaessnypclvpvkwggncqkdrqspinivttkakvdkklgrfffsgydkk
qtwtvqnnghsvmmllenkasisggglpapyqakqlhlhwsdlpykgsehsldgehfame
mhivhekekgtsrnvkeaqdpedeiavlaflveagtqvnegfqplvealsnipkpemstt
maesslldllpkeeklrhyfrylgslttptcdekvvwtvfrepiqlhreqilafsqklyy
dkeqtvsmkdnvrplqqlgqrtviks

    Sequence, based on observed residues (ATOM records): (download) 
    >5jncB (B:)
hwcyevqaessnypclvpvkwggncqkdrqspinivttkakvdkklgrfffsgydkkqtw
tvqnnghsvmmllenkasisggglpapyqakqlhlhwsdlpykgsehsldgehfamemhi
vhekekgtdpedeiavlaflveagtqvnegfqplvealsnipkpemsttmaesslldllp
keeklrhyfrylgslttptcdekvvwtvfrepiqlhreqilafsqklyydkeqtvsmkdn
vrplqqlgqrtviks

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5jncC (C:)
aeshwcyevqaessnypclvpvkwggncqkdrqspinivttkakvdkklgrfffsgydkk
qtwtvqnnghsvmmllenkasisggglpapyqakqlhlhwsdlpykgsehsldgehfame
mhivhekekgtsrnvkeaqdpedeiavlaflveagtqvnegfqplvealsnipkpemstt
maesslldllpkeeklrhyfrylgslttptcdekvvwtvfrepiqlhreqilafsqklyy
dkeqtvsmkdnvrplqqlgqrtviks

    Sequence, based on observed residues (ATOM records): (download) 
    >5jncC (C:)
shwcyevqaessnypclvpvkwggncqkdrqspinivttkakvdkklgrfffsgydkkqt
wtvqnnghsvmmllenkasisggglpapyqakqlhlhwsdlpykgsehsldgehfamemh
ivhekekgtsrnvkeaqdpedeiavlaflveagtqvnegfqplvealsnipkpemsttma
esslldllpkeeklrhyfrylgslttptcdekvvwtvfrepiqlhreqilafsqklyydk
eqtvsmkdnvrplqqlgqrtviks

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5jncD (D:)
aeshwcyevqaessnypclvpvkwggncqkdrqspinivttkakvdkklgrfffsgydkk
qtwtvqnnghsvmmllenkasisggglpapyqakqlhlhwsdlpykgsehsldgehfame
mhivhekekgtsrnvkeaqdpedeiavlaflveagtqvnegfqplvealsnipkpemstt
maesslldllpkeeklrhyfrylgslttptcdekvvwtvfrepiqlhreqilafsqklyy
dkeqtvsmkdnvrplqqlgqrtviks

    Sequence, based on observed residues (ATOM records): (download) 
    >5jncD (D:)
hwcyevqaessnypclvpvkwggncqkdrqspinivttkakvdkklgrfffsgydkkqtw
tvqnnghsvmmllenkasisggglpapyqakqlhlhwsdlpykgsehsldgehfamemhi
vhekekgtsrnvkeaqdpedeiavlaflveagtqvnegfqplvealsnipkpemsttmae
sslldllpkeeklrhyfrylgslttptcdekvvwtvfrepiqlhreqilafsqklyydke
qtvsmkdnvrplqqlgqrtviks