PDB entry 5jgi

View 5jgi on RCSB PDB site
Description: X-ray structure of neuropilin-1 b1 domain complexed with M45 compound
Class: signaling protein
Keywords: SIGNALING PROTEIN, Neuropilin-1, Angiogenesis
Deposited on 2016-04-20, released 2017-05-10
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-05-10, with a file datestamp of 2017-05-05.
Experiment type: XRAY
Resolution: 1.38 Å
R-factor: N/A
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neuropilin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: NRP1, NRP, VEGF165R
    Database cross-references and differences (RAF-indexed):
    • Uniprot O14786 (1-155)
      • initiating methionine (0)
    Domains in SCOPe 2.07: d5jgia1, d5jgia2
  • Chain 'B':
    Compound: Neuropilin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: NRP1, NRP, VEGF165R
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5jgib_
  • Heterogens: AAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5jgiA (A:)
    mfkcmealgmesgeihsdqitassqystnwsaersrlnypengwtpgedsyrewiqvdlg
    llrfvtavgtqgaisketkkkyyvktykidvssngedwitikegnkpvlfqgntnptdvv
    vavfpkplitrfvrikpatwetgismrfevygckit
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5jgiB (B:)
    mfkcmealgmesgeihsdqitassqystnwsaersrlnypengwtpgedsyrewiqvdlg
    llrfvtavgtqgaisketkkkyyvktykidvssngedwitikegnkpvlfqgntnptdvv
    vavfpkplitrfvrikpatwetgismrfevygckit
    

    Sequence, based on observed residues (ATOM records): (download)
    >5jgiB (B:)
    kcmealgmesgeihsdqitassqystnwsaersrlnypengwtpgedsyrewiqvdlgll
    rfvtavgtqgaisketkkkyyvktykidvssngedwitikegnkpvlfqgntnptdvvva
    vfpkplitrfvrikpatwetgismrfevygckit