PDB entry 5jax

View 5jax on RCSB PDB site
Description: PKG I's Carboyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with 8-Br-cGMP
Class: transferase/transferase inhibitor
Keywords: Binding Sites, Cyclic AMP, Cyclic GMP, Cyclic GMP-Dependent Protein Kinase Type II, Mutagenesis, Site-Directed, Protein Binding, analogs, transferase-transferase inhibitor complex
Deposited on 2016-04-12, released 2017-04-19
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-04-19, with a file datestamp of 2017-04-14.
Experiment type: XRAY
Resolution: 1.49 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: cGMP-dependent protein kinase 1
  Species: Homo sapiens [TaxId:9606]
  Gene: PRKG1, PRKG1B, PRKGR1A, PRKGR1B
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q13976 (Start-134)
  Domains in SCOPe 2.06: d5jaxa_
• Heterogens: 6J7, CA, NA, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >5jaxA (A:)
  gstglikhteymeflksvptfqslpeeilskladvleethyengeyiirqgargdtffii
  skgtvnvtredspsedpvflrtlgkgdwfgekalqgedvrtanviaaeavtclvidrdsf
  khligglddvsnkay
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >5jaxA (A:)
  ikhteymeflksvptfqslpeeilskladvleethyengeyiirqgargdtffiiskgtv
  nvtredspsedpvflrtlgkgdwfgekalqgedvrtanviaaeavtclvidrdsfkhlig
  glddvsnkay