PDB entry 5ja7
View 5ja7 on RCSB PDB site
Description: Human cathepsin K mutant C25S in complex with the allosteric effector NSC94914
Class: hydrolase
Keywords: allostery cysteine peptidase proteolysis enzyme regulation collagenase, hydrolase
Deposited on
2016-04-12, released
2016-11-30
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-01-11, with a file datestamp of
2017-01-06.
Experiment type: XRAY
Resolution: 1.61 Å
R-factor: N/A
AEROSPACI score: 0.43
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: cathepsin k
Species: Homo sapiens [TaxId:9606]
Gene: CTSK, CTSO, CTSO2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5ja7a_ - Chain 'B':
Compound: cathepsin k
Species: Homo sapiens [TaxId:9606]
Gene: CTSK, CTSO, CTSO2
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5ja7b_ - Heterogens: 6HM, SO4, GOL, ACT, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5ja7A (A:)
yipewegrapdsvdyrkkgyvtpvknqgqcgsswafssvgalegqlkkktgkllnlspqn
lvdcvsendgcgggymtnafqyvqknrgidsedaypyvgqeescmynptgkaakcrgyre
ipegnekalkravarvgpvsvaidasltsfqfyskgvyydescnsdnlnhavlavgygiq
kgnkhwiiknswgenwgnkgyilmarnknnacgianlasfpkm
Sequence, based on observed residues (ATOM records): (download)
>5ja7A (A:)
ipewegrapdsvdyrkkgyvtpvknqgqcgsswafssvgalegqlkkktgkllnlspqnl
vdcvsendgcgggymtnafqyvqknrgidsedaypyvgqeescmynptgkaakcrgyrei
pegnekalkravarvgpvsvaidasltsfqfyskgvyydescnsdnlnhavlavgygiqk
gnkhwiiknswgenwgnkgyilmarnknnacgianlasfpkm
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>5ja7B (B:)
yipewegrapdsvdyrkkgyvtpvknqgqcgsswafssvgalegqlkkktgkllnlspqn
lvdcvsendgcgggymtnafqyvqknrgidsedaypyvgqeescmynptgkaakcrgyre
ipegnekalkravarvgpvsvaidasltsfqfyskgvyydescnsdnlnhavlavgygiq
kgnkhwiiknswgenwgnkgyilmarnknnacgianlasfpkm