PDB entry 5iuh

View 5iuh on RCSB PDB site
Description: Crystal Structure of the Anaplastic Lymphoma Kinase (ALK) in complex with 5d
Class: transferase
Keywords: catalytic domain, transferase
Deposited on 2016-03-18, released 2016-05-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-05-18, with a file datestamp of 2016-05-13.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ALK tyrosine kinase receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: ALK
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UM73
      • engineered mutation (13)
    Domains in SCOPe 2.08: d5iuha_
  • Heterogens: 34Y, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5iuhA (A:)
rtstimtdynpnysfagktssisdlkevprknitlirglghgafgevyegqvsgmpndps
plqvavktlpevcseqdeldflmealiiskfnhqnivrcigvslqslprfillelmaggd
lksflretrprpsqpsslamldllhvardiacgcqyleenhfihrdiaarnclltcpgpg
rvakigdfgmardiyrasyyrkggcamlpvkwmppeafmegiftsktdtwsfgvllweif
slgympypsksnqevlefvtsggrmdppkncpgpvyrimtqcwqhqpedrpnfaiileri
eyctqdpdvintalpieygplveeeek

    Sequence, based on observed residues (ATOM records): (download) 
    >5iuhA (A:)
npnysfagktssisdlkevprknitlirglgevyegqvsgplqvavktlpevcseqdeld
flmealiiskfnhqnivrcigvslqslprfillelmaggdlksflretrprpsslamldl
lhvardiacgcqyleenhfihrdiaarnclltcpgpgrvakigdfgmacamlpvkwmppe
afmegiftsktdtwsfgvllweifslgympypsksnqevlefvtsggrmdppkncpgpvy
rimtqcwqhqpedrpnfaiilerieyctqdpdvintalpieygpl