PDB entry 5iue

View 5iue on RCSB PDB site
Description: Human leukocyte antigen F (HLA-F) presents peptides and regulates immunity through interactions with NK-cell receptors
Class: protein binding
Keywords: MHC-Ib, IMMUNE SYSTEM, PEPTIDE BINDING PROTEIN, PROTEIN BINDING
Deposited on 2016-03-17, released 2017-06-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.62 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cDNA FLJ39643 fis, clone SMINT2004023, highly similar to HLA class I histocompatibility antigen, alphachain F
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5iuea1, d5iuea2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (Start-167)
      • conflict (68)
    Domains in SCOPe 2.08: d5iueb_
  • Chain 'E':
    Compound: cDNA FLJ39643 fis, clone SMINT2004023, highly similar to HLA class I histocompatibility antigen, alphachain F
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5iuee1, d5iuee2
  • Chain 'F':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5iuef_
  • Chain 'G':
    Compound: cDNA FLJ39643 fis, clone SMINT2004023, highly similar to HLA class I histocompatibility antigen, alphachain F
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5iueg1, d5iueg2
  • Chain 'H':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769
      • conflict (68)
    Domains in SCOPe 2.08: d5iueh_
  • Chain 'I':
    Compound: cDNA FLJ39643 fis, clone SMINT2004023, highly similar to HLA class I histocompatibility antigen, alphachain F
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5iuei1, d5iuei2
  • Chain 'J':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769
      • conflict (68)
    Domains in SCOPe 2.08: d5iuej_
  • Chain 'K':
    Compound: Peptide LEU-ILE-LEU-ARG-TRP-GLU-GLN-ASP
    Species: Trichoplusia ni [TaxId:7111]
    Database cross-references and differences (RAF-indexed):
    • PDB 5IUE (Start-7)
  • Chain 'L':
    Compound: Peptide LEU-ILE-LEU-ARG-TRP-GLU-GLN-ASP
    Species: Trichoplusia ni [TaxId:7111]
    Database cross-references and differences (RAF-indexed):
    • PDB 5IUE (Start-7)
  • Chain 'M':
    Compound: Peptide LEU-ILE-LEU-ARG-TRP-GLU-GLN-ASP
    Species: Trichoplusia ni [TaxId:7111]
    Database cross-references and differences (RAF-indexed):
    • PDB 5IUE (Start-7)
  • Chain 'N':
    Compound: Peptide LEU-ILE-LEU-ARG-TRP-GLU-GLN-ASP
    Species: Trichoplusia ni [TaxId:7111]
    Database cross-references and differences (RAF-indexed):
    • PDB 5IUE (0-7)
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5iueA (A:)
gshslryfstavsrpgrgepryiaveyvddtqflrfdsdaaiprmeprepwveqegpqyw
ewttgyakanaqtdrvalrnllrrynqseagshtlqgmngcdmgpdgrllrgyhqhaydg
kdyislnedlrswtaadtvaqitqrfyeaeeyaeefrtylegeclellrrylengketlq
radppkahvahhpisdheatlrcwalgfypaeitltwqrdgeeqtqdtelvetrpagdgt
fqkwaavvvpsgeeqrytchvqheglpqplilrweqspqptipi

    Sequence, based on observed residues (ATOM records): (download) 
    >5iueA (A:)
shslryfstavsrpgrgepryiaveyvddtqflrfdsdaaiprmeprepwveqegpqywe
wttgyakanaqtdrvalrnllrrynqseagshtlqgmngcdmgpdgrllrgyhqhaydgk
dyislnedlrswtaadtvaqitqrfyeaeeyaeefrtylegeclellrrylengketlqr
adppkahvahhpisdheatlrcwalgfypaeitltwqrdgeeqtqdtelvetrpagdgtf
qkwaavvvpsgeeqrytchvqheglpqplilrweq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5iueB (B:)
mllvnqshqgfnkehtskmvsaivlyvllaaaahsafaadlhhhhhhhhgsgglevlfqg
pefggsadpiqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekveh
sdlsfskdwsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdmggggsggsgsgg
gs

    Sequence, based on observed residues (ATOM records): (download) 
    >5iueB (B:)
piqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5iueE (E:)
gshslryfstavsrpgrgepryiaveyvddtqflrfdsdaaiprmeprepwveqegpqyw
ewttgyakanaqtdrvalrnllrrynqseagshtlqgmngcdmgpdgrllrgyhqhaydg
kdyislnedlrswtaadtvaqitqrfyeaeeyaeefrtylegeclellrrylengketlq
radppkahvahhpisdheatlrcwalgfypaeitltwqrdgeeqtqdtelvetrpagdgt
fqkwaavvvpsgeeqrytchvqheglpqplilrweqspqptipi

    Sequence, based on observed residues (ATOM records): (download) 
    >5iueE (E:)
shslryfstavsrpgrgepryiaveyvddtqflrfdsdaaiprmeprepwveqegpqywe
wttgyakanaqtdrvalrnllrrynqseagshtlqgmngcdmgpdgrllrgyhqhaydgk
dyislnedlrswtaadtvaqitqrfyeaeeyaeefrtylegeclellrrylengketlqr
adppkahvahhpisdheatlrcwalgfypaeitltwqrdgeeqtqdtelvetrpagdgtf
qkwaavvvpsgeeqrytchvqheglpqplilrweq

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >5iueF (F:)
mllvnqshqgfnkehtskmvsaivlyvllaaaahsafaadlhhhhhhhhgsgglevlfqg
pefggsadpiqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekveh
sdlsfskdwsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdmggggsggsgsgg
gs

    Sequence, based on observed residues (ATOM records): (download) 
    >5iueF (F:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >5iueG (G:)
gshslryfstavsrpgrgepryiaveyvddtqflrfdsdaaiprmeprepwveqegpqyw
ewttgyakanaqtdrvalrnllrrynqseagshtlqgmngcdmgpdgrllrgyhqhaydg
kdyislnedlrswtaadtvaqitqrfyeaeeyaeefrtylegeclellrrylengketlq
radppkahvahhpisdheatlrcwalgfypaeitltwqrdgeeqtqdtelvetrpagdgt
fqkwaavvvpsgeeqrytchvqheglpqplilrweqspqptipi

    Sequence, based on observed residues (ATOM records): (download) 
    >5iueG (G:)
shslryfstavsrpgrgepryiaveyvddtqflrfdsdaaiprmeprepwveqegpqywe
wttgyakanaqtdrvalrnllrrynqseagshtlqgmngcdmgpdgrllrgyhqhaydgk
dyislnedlrswtaadtvaqitqrfyeaeeyaeefrtylegeclellrrylengketlqr
adppkahvahhpisdheatlrcwalgfypaeitltwqrdgeeqtqdtelvetrpagdgtf
qkwaavvvpsgeeqrytchvqheglpqplilrwe

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >5iueH (H:)
mllvnqshqgfnkehtskmvsaivlyvllaaaahsafaadlhhhhhhhhgsgglevlfqg
pefggsadpiqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekveh
sdlsfskdwsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdmggggsggsgsgg
gs

    Sequence, based on observed residues (ATOM records): (download) 
    >5iueH (H:)
piqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrd

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >5iueI (I:)
gshslryfstavsrpgrgepryiaveyvddtqflrfdsdaaiprmeprepwveqegpqyw
ewttgyakanaqtdrvalrnllrrynqseagshtlqgmngcdmgpdgrllrgyhqhaydg
kdyislnedlrswtaadtvaqitqrfyeaeeyaeefrtylegeclellrrylengketlq
radppkahvahhpisdheatlrcwalgfypaeitltwqrdgeeqtqdtelvetrpagdgt
fqkwaavvvpsgeeqrytchvqheglpqplilrweqspqptipi

    Sequence, based on observed residues (ATOM records): (download) 
    >5iueI (I:)
gshslryfstavsrpgrgepryiaveyvddtqflrfdsdaaiprmeprepwveqegpqyw
ewttgyakanaqtdrvalrnllrrynqseagshtlqgmngcdmgpdgrllrgyhqhaydg
kdyislnedlrswtaadtvaqitqrfyeaeeyaeefrtylegeclellrrylengketlq
radppkahvahhpisdheatlrcwalgfypaeitltwqrdgeeqtqdtelvetrpagdgt
fqkwaavvvpsgeeqrytchvqheglpqplilrwe

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >5iueJ (J:)
mllvnqshqgfnkehtskmvsaivlyvllaaaahsafaadlhhhhhhhhgsgglevlfqg
pefggsadpiqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekveh
sdlsfskdwsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdmggggsggsgsgg
gs

    Sequence, based on observed residues (ATOM records): (download) 
    >5iueJ (J:)
piqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrd

  • Chain 'K':
    No sequence available.

  • Chain 'L':
    No sequence available.

  • Chain 'M':
    No sequence available.

  • Chain 'N':
    No sequence available.