PDB entry 5isi

View 5isi on RCSB PDB site
Description: crystal structure of mouse carm1 in complex with inhibitor sa0920 (5'- amino-5'-deoxyadenosine)
Deposited on 2016-03-15, released 2017-03-15
The last revision was dated 2017-03-15, with a file datestamp of 2017-03-10.
Experiment type: XRAY
Resolution: 2.74 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: histone-arginine methyltransferase carm1
    Species: Mus musculus [TaxId:10090]
    Gene: Carm1, Prmt4
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: histone-arginine methyltransferase carm1
    Species: Mus musculus [TaxId:10090]
    Gene: Carm1, Prmt4
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: histone-arginine methyltransferase carm1
    Species: Mus musculus [TaxId:10090]
    Gene: Carm1, Prmt4
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: histone-arginine methyltransferase carm1
    Species: Mus musculus [TaxId:10090]
    Gene: Carm1, Prmt4
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 5N5, EDO, DXE, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.07, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >5isiA (A:)
    ghmghtlersvfserteessavqyfqfygylsqqqnmmqdyvrtgtyqrailqnhtdfkd
    kivldvgcgsgilsffaaqagarkiyaveastmaqhaevlvksnnltdrivvipgkveev
    slpeqvdiiisepmgymlfnermlesylhakkylkpsgnmfptigdvhlapftdeqlyme
    qftkanfwyqpsfhgvdlsalrgaavdeyfrqpvvdtfdirilmaksvkytvnfleakeg
    dlhrieipfkfhmlhsglvhglafwfdvafigsimtvwlstapteplthwyqvrclfqsp
    lfakagdtlsgtclliankrqsydisivaqvdqtgskssnlldlknpffrytgttpsppp
    g
    

    Sequence, based on observed residues (ATOM records):
    >5isiA (A:)
    svfserteessavqyfqfygylsqqqnmmqdyvrtgtyqrailqnhtdfkdkivldvgcg
    sgilsffaaqagarkiyaveastmaqhaevlvksnnltdrivvipgkveevslpeqvdii
    isepmgymlfnermlesylhakkylkpsgnmfptigdvhlapftdeqlymeqftkanfwy
    qpsfhgvdlsalrgaavdeyfrqpvvdtfdirilmaksvkytvnfleakegdlhrieipf
    kfhmlhsglvhglafwfdvafigsimtvwlstapteplthwyqvrclfqsplfakagdtl
    sgtclliankrqsydisivaqvdqtgskssnlldlknpffryt
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >5isiB (B:)
    ghmghtlersvfserteessavqyfqfygylsqqqnmmqdyvrtgtyqrailqnhtdfkd
    kivldvgcgsgilsffaaqagarkiyaveastmaqhaevlvksnnltdrivvipgkveev
    slpeqvdiiisepmgymlfnermlesylhakkylkpsgnmfptigdvhlapftdeqlyme
    qftkanfwyqpsfhgvdlsalrgaavdeyfrqpvvdtfdirilmaksvkytvnfleakeg
    dlhrieipfkfhmlhsglvhglafwfdvafigsimtvwlstapteplthwyqvrclfqsp
    lfakagdtlsgtclliankrqsydisivaqvdqtgskssnlldlknpffrytgttpsppp
    g
    

    Sequence, based on observed residues (ATOM records):
    >5isiB (B:)
    svfserteessavqyfqfygylsqqqnmmqdyvrtgtyqrailqnhtdfkdkivldvgcg
    sgilsffaaqagarkiyaveastmaqhaevlvksnnltdrivvipgkveevslpeqvdii
    isepmgymlfnermlesylhakkylkpsgnmfptigdvhlapftdeqlymeqftkanfwy
    qpsfhgvdlsalrgaavdeyfrqpvvdtfdirilmaksvkytvnfleakegdlhrieipf
    kfhmlhsglvhglafwfdvafigsimtvwlstapteplthwyqvrclfqsplfakagdtl
    sgtclliankrqsydisivaqvdqtgskssnlldlknpffry
    

  • Chain 'C':
    Sequence, based on SEQRES records:
    >5isiC (C:)
    ghmghtlersvfserteessavqyfqfygylsqqqnmmqdyvrtgtyqrailqnhtdfkd
    kivldvgcgsgilsffaaqagarkiyaveastmaqhaevlvksnnltdrivvipgkveev
    slpeqvdiiisepmgymlfnermlesylhakkylkpsgnmfptigdvhlapftdeqlyme
    qftkanfwyqpsfhgvdlsalrgaavdeyfrqpvvdtfdirilmaksvkytvnfleakeg
    dlhrieipfkfhmlhsglvhglafwfdvafigsimtvwlstapteplthwyqvrclfqsp
    lfakagdtlsgtclliankrqsydisivaqvdqtgskssnlldlknpffrytgttpsppp
    g
    

    Sequence, based on observed residues (ATOM records):
    >5isiC (C:)
    svfserteessavqyfqfygylsqqqnmmqdyvrtgtyqrailqnhtdfkdkivldvgcg
    sgilsffaaqagarkiyaveastmaqhaevlvksnnltdrivvipgkveevslpeqvdii
    isepmgymlfnermlesylhakkylkpsgnmfptigdvhlapftdeqlymeqftkanfwy
    qpsfhgvdlsalrgaavdeyfrqpvvdtfdirilmaksvkytvnfleakegdlhrieipf
    kfhmlhsglvhglafwfdvafigsimtvwlstapteplthwyqvrclfqsplfakagdtl
    sgtclliankrqsydisivaqvdqtgskssnlldlknpffryt
    

  • Chain 'D':
    Sequence, based on SEQRES records:
    >5isiD (D:)
    ghmghtlersvfserteessavqyfqfygylsqqqnmmqdyvrtgtyqrailqnhtdfkd
    kivldvgcgsgilsffaaqagarkiyaveastmaqhaevlvksnnltdrivvipgkveev
    slpeqvdiiisepmgymlfnermlesylhakkylkpsgnmfptigdvhlapftdeqlyme
    qftkanfwyqpsfhgvdlsalrgaavdeyfrqpvvdtfdirilmaksvkytvnfleakeg
    dlhrieipfkfhmlhsglvhglafwfdvafigsimtvwlstapteplthwyqvrclfqsp
    lfakagdtlsgtclliankrqsydisivaqvdqtgskssnlldlknpffrytgttpsppp
    g
    

    Sequence, based on observed residues (ATOM records):
    >5isiD (D:)
    svfserteessavqyfqfygylsqqqnmmqdyvrtgtyqrailqnhtdfkdkivldvgcg
    sgilsffaaqagarkiyaveastmaqhaevlvksnnltdrivvipgkveevslpeqvdii
    isepmgymlfnermlesylhakkylkpsgnmfptigdvhlapftdeqlymeqftkanfwy
    qpsfhgvdlsalrgaavdeyfrqpvvdtfdirilmaksvkytvnfleakegdlhrieipf
    kfhmlhsglvhglafwfdvafigsimtvwlstapteplthwyqvrclfqsplfakagdtl
    sgtclliankrqsydisivaqvdqtgskssnlldlknpffryt