PDB entry 5ing

View 5ing on RCSB PDB site
Description: A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender unit
Class: transferase
Keywords: Acyl-CoA, Crotonase, Polyketide, Extender-Unit, TRANSFERASE
Deposited on 2016-03-07, released 2016-12-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-01, with a file datestamp of 2019-12-27.
Experiment type: XRAY
Resolution: 2.45 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Putative carboxyl transferase
    Species: Streptomyces ambofaciens ATCC 23877 [TaxId:278992]
    Gene: SAM23877_7108, SAMR0483
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5inga1, d5inga2
  • Chain 'B':
    Compound: Putative carboxyl transferase
    Species: Streptomyces ambofaciens ATCC 23877 [TaxId:278992]
    Gene: SAM23877_7108, SAMR0483
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ingb1, d5ingb2
  • Chain 'C':
    Compound: Putative carboxyl transferase
    Species: Streptomyces ambofaciens ATCC 23877 [TaxId:278992]
    Gene: SAM23877_7108, SAMR0483
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ingc1, d5ingc2
  • Chain 'D':
    Compound: Putative carboxyl transferase
    Species: Streptomyces ambofaciens ATCC 23877 [TaxId:278992]
    Gene: SAM23877_7108, SAMR0483
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ingd1, d5ingd2
  • Chain 'E':
    Compound: Putative carboxyl transferase
    Species: Streptomyces ambofaciens ATCC 23877 [TaxId:278992]
    Gene: SAM23877_7108, SAMR0483
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5inge1, d5inge2
  • Chain 'F':
    Compound: Putative carboxyl transferase
    Species: Streptomyces ambofaciens ATCC 23877 [TaxId:278992]
    Gene: SAM23877_7108, SAMR0483
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5ingf1, d5ingf2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5ingA (A:)
mgsshhhhhhssglvprgshmasdstenlyfqgidpftmslqepvspveesptstadria
dlaarheeavvlaekkaadrqhlkgkltararidllldpgsfveldefvrhrtveagipr
pygdgvvtghgtidgrqvcvfshdfttlggsmgeafgskvvkiydfamsvgcpviginds
ggariqegvmsiayytelgvrnvhssgvipqislimgpcaggsvyspaltdftvmvkdis
ymfvtgpevvsavmgeqvtaeqlggpavhaevsgnahyvgddeqdaiswvqtllgylppn
nldpapvydhdcapgiteadlaldtvipdseqqvydmadvitavlddgdyleihpdfarn
iicalgrveghsvavvanqprhlagvldidasekaarfirfcdsfnipvltfmdvpgylp
gvgqehqgiirrgiklfyayaestvpkitvitrkaygggyavmgsrqigadrvmawptae
iavmgansavpilhrrelaavppeeraavkenlvddyrrrfgnpyeaaahgyvdmvisps
rtryevaralaslrnkrqarparkhgnipl

    Sequence, based on observed residues (ATOM records): (download) 
    >5ingA (A:)
esptstadriadlaarheeavvlaekkaadrqhlkgkltararidllldpgsfveldefv
rhrtprpygdgvvtghgtidgrqvcvfshdfttlggsmgeafgskvvkiydfamsvgcpv
igindsggariqegvmsiayytelgvrnvhssgvipqislimgpcaggsvyspaltdftv
mvkdisymfvtgpevvsavmgeqvtaeqlggpavhaevsgnahyvgddeqdaiswvqtll
gylppnnldpapvydhdcapgiteadlaldtvipdseqqvydmadvitavlddgdyleih
pdfarniicalgrveghsvavvanqprhlagvldidasekaarfirfcdsfnipvltfmd
vpgylpgvgqehqgiirrgiklfyayaestvpkitvitrkaygggyavmgsrqigadrvm
awptaeiavmgansavpilvddyrrrfgnpyeaaahgyvdmvispsrtryevaralaslr
nkrqarparkhgnipl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5ingB (B:)
mgsshhhhhhssglvprgshmasdstenlyfqgidpftmslqepvspveesptstadria
dlaarheeavvlaekkaadrqhlkgkltararidllldpgsfveldefvrhrtveagipr
pygdgvvtghgtidgrqvcvfshdfttlggsmgeafgskvvkiydfamsvgcpviginds
ggariqegvmsiayytelgvrnvhssgvipqislimgpcaggsvyspaltdftvmvkdis
ymfvtgpevvsavmgeqvtaeqlggpavhaevsgnahyvgddeqdaiswvqtllgylppn
nldpapvydhdcapgiteadlaldtvipdseqqvydmadvitavlddgdyleihpdfarn
iicalgrveghsvavvanqprhlagvldidasekaarfirfcdsfnipvltfmdvpgylp
gvgqehqgiirrgiklfyayaestvpkitvitrkaygggyavmgsrqigadrvmawptae
iavmgansavpilhrrelaavppeeraavkenlvddyrrrfgnpyeaaahgyvdmvisps
rtryevaralaslrnkrqarparkhgnipl

    Sequence, based on observed residues (ATOM records): (download) 
    >5ingB (B:)
ptstadriadlaarheeavvlaekkaadrqhlkgkltararidllldpgsfveldefvrh
rtveagiprpygdgvvtghgtidgrqvcvfshdfttlggsmgeafgskvvkiydfamsvg
cpvigindsggariqegvmsiayytelgvrnvhssgvipqislimgpcaggsvyspaltd
ftvmvkdisymfvtgpevvsavmgeqvtaeqlggpavhaevsgnahyvgddeqdaiswvq
tllgylppnnldpapvydhdcapgiteadlaldtvipdseqqvydmadvitavlddgdyl
eihpdfarniicalgrveghsvavvanqprhlagvldidasekaarfirfcdsfnipvlt
fmdvpgylpgvgqehqgiirrgiklfyayaestvpkitvitrkaygggyavmgsrqigad
rvmawptaeiavmgansavlvddyrrrfgnpyeaaahgyvdmvispsrtryevaralasl
rnkrqarparkhgnipl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5ingC (C:)
mgsshhhhhhssglvprgshmasdstenlyfqgidpftmslqepvspveesptstadria
dlaarheeavvlaekkaadrqhlkgkltararidllldpgsfveldefvrhrtveagipr
pygdgvvtghgtidgrqvcvfshdfttlggsmgeafgskvvkiydfamsvgcpviginds
ggariqegvmsiayytelgvrnvhssgvipqislimgpcaggsvyspaltdftvmvkdis
ymfvtgpevvsavmgeqvtaeqlggpavhaevsgnahyvgddeqdaiswvqtllgylppn
nldpapvydhdcapgiteadlaldtvipdseqqvydmadvitavlddgdyleihpdfarn
iicalgrveghsvavvanqprhlagvldidasekaarfirfcdsfnipvltfmdvpgylp
gvgqehqgiirrgiklfyayaestvpkitvitrkaygggyavmgsrqigadrvmawptae
iavmgansavpilhrrelaavppeeraavkenlvddyrrrfgnpyeaaahgyvdmvisps
rtryevaralaslrnkrqarparkhgnipl

    Sequence, based on observed residues (ATOM records): (download) 
    >5ingC (C:)
ptstadriadlaarheeavvlaekkaadrqhlkgkltararidllldpgsfveldefvrh
rtveagiprpygdgvvtghgtidgrqvcvfshdfttlggsmgeafgskvvkiydfamsvg
cpvigindsggariqegvmsiayytelgvrnvhssgvipqislimgpcaggsvyspaltd
ftvmvkdisymfvtgpevvsavmgeqvtaeqlggpavhaevsgnahyvgddeqdaiswvq
tllgylppnnldpapvydhdcapgiteadlaldtvipdseqqvydmadvitavlddgdyl
eihpdfarniicalgrveghsvavvanqprhlagvldidasekaarfirfcdsfnipvlt
fmdvpgylpgvgqehqgiirrgiklfyayaestvpkitvitrkaygggyavmgsrqigad
rvmawptaeiavmgansavaavkenlvddyrrrfgnpyeaaahgyvdmvispsrtryeva
ralaslrnkrqarparkhgnipl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5ingD (D:)
mgsshhhhhhssglvprgshmasdstenlyfqgidpftmslqepvspveesptstadria
dlaarheeavvlaekkaadrqhlkgkltararidllldpgsfveldefvrhrtveagipr
pygdgvvtghgtidgrqvcvfshdfttlggsmgeafgskvvkiydfamsvgcpviginds
ggariqegvmsiayytelgvrnvhssgvipqislimgpcaggsvyspaltdftvmvkdis
ymfvtgpevvsavmgeqvtaeqlggpavhaevsgnahyvgddeqdaiswvqtllgylppn
nldpapvydhdcapgiteadlaldtvipdseqqvydmadvitavlddgdyleihpdfarn
iicalgrveghsvavvanqprhlagvldidasekaarfirfcdsfnipvltfmdvpgylp
gvgqehqgiirrgiklfyayaestvpkitvitrkaygggyavmgsrqigadrvmawptae
iavmgansavpilhrrelaavppeeraavkenlvddyrrrfgnpyeaaahgyvdmvisps
rtryevaralaslrnkrqarparkhgnipl

    Sequence, based on observed residues (ATOM records): (download) 
    >5ingD (D:)
stadriadlaarheeavvlaekkaadrqhlkgkltararidllldpgsfveldefvrhrt
veagiprpygdgvvtghgtidgrqvcvfshdfttlggsmgeafgskvvkiydfamsvgcp
vigindsggariqegvmsiayytelgvrnvhssgvipqislimgpcaggsvyspaltdft
vmvkdisymfvtgpevvsavmgeqvtaeqlggpavhaevsgnahyvgddeqdaiswvqtl
lgylppnnldpapvydhdcapgiteadlaldtvipdseqqvydmadvitavlddgdylei
hpdfarniicalgrveghsvavvanqprhlagvldidasekaarfirfcdsfnipvltfm
dvpgylpgvgqehqgiirrgiklfyayaestvpkitvitrkaygggyavmgsrqigadrv
mawptaeiavmganyrrrfgnpyeaaahgyvdmvispsrtryevaralaslrnkrqarpa
rkhgnipl

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5ingE (E:)
mgsshhhhhhssglvprgshmasdstenlyfqgidpftmslqepvspveesptstadria
dlaarheeavvlaekkaadrqhlkgkltararidllldpgsfveldefvrhrtveagipr
pygdgvvtghgtidgrqvcvfshdfttlggsmgeafgskvvkiydfamsvgcpviginds
ggariqegvmsiayytelgvrnvhssgvipqislimgpcaggsvyspaltdftvmvkdis
ymfvtgpevvsavmgeqvtaeqlggpavhaevsgnahyvgddeqdaiswvqtllgylppn
nldpapvydhdcapgiteadlaldtvipdseqqvydmadvitavlddgdyleihpdfarn
iicalgrveghsvavvanqprhlagvldidasekaarfirfcdsfnipvltfmdvpgylp
gvgqehqgiirrgiklfyayaestvpkitvitrkaygggyavmgsrqigadrvmawptae
iavmgansavpilhrrelaavppeeraavkenlvddyrrrfgnpyeaaahgyvdmvisps
rtryevaralaslrnkrqarparkhgnipl

    Sequence, based on observed residues (ATOM records): (download) 
    >5ingE (E:)
ptstadriadlaarheeavvlaekkaadrqhlkgkltararidllldpgsfveldefvrh
rtvgiprpygdgvvtghgtidgrqvcvfshdfttlggsmgeafgskvvkiydfamsvgcp
vigindsggariqegvmsiayytelgvrnvhssgvipqislimgpcaggsvyspaltdft
vmvkdisymfvtgpevvsageqvtaeqlggpavhaevsgnahyvgddeqdaiswvqtllg
ylppnnldpapvydhdcapgiteadlaldtvipdseqqvydmadvitavlddgdyleihp
dfarniicalgrveghsvavvanqprhlagvldidasekaarfirfcdsfnipvltfmdv
pgylpgvgqehqgiirrgiklfyayaestvpkitvitrkaygggyavmgsrqigadrvma
wptaeiavmgansanlvddyrrrfgnpyeaaahgyvdmvispsrtryevaralaslrnkr
qarparkhgnipl

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >5ingF (F:)
mgsshhhhhhssglvprgshmasdstenlyfqgidpftmslqepvspveesptstadria
dlaarheeavvlaekkaadrqhlkgkltararidllldpgsfveldefvrhrtveagipr
pygdgvvtghgtidgrqvcvfshdfttlggsmgeafgskvvkiydfamsvgcpviginds
ggariqegvmsiayytelgvrnvhssgvipqislimgpcaggsvyspaltdftvmvkdis
ymfvtgpevvsavmgeqvtaeqlggpavhaevsgnahyvgddeqdaiswvqtllgylppn
nldpapvydhdcapgiteadlaldtvipdseqqvydmadvitavlddgdyleihpdfarn
iicalgrveghsvavvanqprhlagvldidasekaarfirfcdsfnipvltfmdvpgylp
gvgqehqgiirrgiklfyayaestvpkitvitrkaygggyavmgsrqigadrvmawptae
iavmgansavpilhrrelaavppeeraavkenlvddyrrrfgnpyeaaahgyvdmvisps
rtryevaralaslrnkrqarparkhgnipl

    Sequence, based on observed residues (ATOM records): (download) 
    >5ingF (F:)
tstadriadlaarheeavvlaekkaadrqhlkgkltararidllldpgsfveldefvrhr
prpygdgvvtghgtidgrqvcvfshdfttlggsmgeafgskvvkiydfamsvgcpvigin
dsggariqegvmsiayytelgvrnvhssgvipqislimgpcaggsvyspaltdftvmvkd
isymfvtgpevvsavmqvtaeqlggpavhaevsgnahyvgddeqdaiswvqtllgylppn
nldpapvydhdcapgiteadlaldtvipdseqqvydmadvitavlddgdyleihpdfarn
iicalgrveghsvavvanqprhlagvldidasekaarfirfcdsfnipvltfmdvpgylp
gvgqehqgiirrgiklfyayaestvpkitvitrkaygggyavmgsrqigadrvmawptae
iavmgansavrrrfgnpyeaaahgyvdmvispsrtryevaralaslrnkrqarparkhgn
ipl