PDB entry 5ig3

View 5ig3 on RCSB PDB site
Description: Crystal structure of the human CaMKII-alpha hub
Class: transferase
Keywords: Ca2+/CaM-dependent kinase alpha, hub, TRANSFERASE
Deposited on 2016-02-26, released 2016-03-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-20, with a file datestamp of 2019-11-15.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Calcium/calmodulin-dependent protein kinase type II subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: CAMK2A, CAMKA, KIAA0968
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UQM7 (22-End)
      • expression tag (6-21)
    Domains in SCOPe 2.08: d5ig3a1, d5ig3a2
  • Chain 'B':
    Compound: Calcium/calmodulin-dependent protein kinase type II subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: CAMK2A, CAMKA, KIAA0968
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UQM7 (22-End)
      • expression tag (21)
    Domains in SCOPe 2.08: d5ig3b1, d5ig3b2
  • Chain 'C':
    Compound: Calcium/calmodulin-dependent protein kinase type II subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: CAMK2A, CAMKA, KIAA0968
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UQM7 (22-End)
      • expression tag (8-11)
      • expression tag (20-21)
    Domains in SCOPe 2.08: d5ig3c1, d5ig3c2
  • Chain 'D':
    Compound: Calcium/calmodulin-dependent protein kinase type II subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: CAMK2A, CAMKA, KIAA0968
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UQM7 (22-End)
      • expression tag (8-10)
      • expression tag (21)
    Domains in SCOPe 2.08: d5ig3d1, d5ig3d2
  • Chain 'E':
    Compound: Calcium/calmodulin-dependent protein kinase type II subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: CAMK2A, CAMKA, KIAA0968
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UQM7 (22-End)
      • expression tag (20-21)
    Domains in SCOPe 2.08: d5ig3e1, d5ig3e2
  • Chain 'F':
    Compound: Calcium/calmodulin-dependent protein kinase type II subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: CAMK2A, CAMKA, KIAA0968
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UQM7 (22-End)
      • expression tag (21)
    Domains in SCOPe 2.08: d5ig3f1, d5ig3f2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5ig3A (A:)
gsshhhhhhssglevlfqgphmvrkqeiikvteqlieaisngdfesytkmcdpgmtafep
ealgnlvegldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldagg
iprtaqseetrvwhrrdgkwqivhfhrsgapsv

    Sequence, based on observed residues (ATOM records): (download) 
    >5ig3A (A:)
hhhssglevlfqgphmvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnl
vegldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldaggiprtaq
seetrvwhrrdgkwqivhfhrsga

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5ig3B (B:)
gsshhhhhhssglevlfqgphmvrkqeiikvteqlieaisngdfesytkmcdpgmtafep
ealgnlvegldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldagg
iprtaqseetrvwhrrdgkwqivhfhrsgapsv

    Sequence, based on observed residues (ATOM records): (download) 
    >5ig3B (B:)
mvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlvegldfhrfyfenlw
skpvhttilnphihlmgdesaciayiritqyldaggiprtaqseetrvwhrrdgkwqivh
fhrsgap

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5ig3C (C:)
gsshhhhhhssglevlfqgphmvrkqeiikvteqlieaisngdfesytkmcdpgmtafep
ealgnlvegldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldagg
iprtaqseetrvwhrrdgkwqivhfhrsgapsv

    Sequence, based on observed residues (ATOM records): (download) 
    >5ig3C (C:)
hssghmvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlvegldfhrfy
fenlwsskpvhttilnphihlmgdesaciayiritqyldaggiprtaqseetrvwhrrdg
kwqivhfhrsga

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5ig3D (D:)
gsshhhhhhssglevlfqgphmvrkqeiikvteqlieaisngdfesytkmcdpgmtafep
ealgnlvegldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldagg
iprtaqseetrvwhrrdgkwqivhfhrsgapsv

    Sequence, based on observed residues (ATOM records): (download) 
    >5ig3D (D:)
hssmvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlvegldfhrfyfe
nlpvhttilnphihlmgdesaciayiritqyldaggiprtaqseetrvwhrrdgkwqivh
fhrsgap

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5ig3E (E:)
gsshhhhhhssglevlfqgphmvrkqeiikvteqlieaisngdfesytkmcdpgmtafep
ealgnlvegldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldagg
iprtaqseetrvwhrrdgkwqivhfhrsgapsv

    Sequence, based on observed residues (ATOM records): (download) 
    >5ig3E (E:)
hmvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlvegldfhrfyfenl
pvhttilnphihlmgdesaciayiritqyldaggiprtaqseetrvwhrrdgkwqivhfh
rsgap

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >5ig3F (F:)
gsshhhhhhssglevlfqgphmvrkqeiikvteqlieaisngdfesytkmcdpgmtafep
ealgnlvegldfhrfyfenlwsrnskpvhttilnphihlmgdesaciayiritqyldagg
iprtaqseetrvwhrrdgkwqivhfhrsgapsv

    Sequence, based on observed residues (ATOM records): (download) 
    >5ig3F (F:)
mvrkqeiikvteqlieaisngdfesytkmcdpgmtafepealgnlvegldfhrfyfenkp
vhttilnphihlmgdesaciayiritqyldaggiprtaqseetrvwhrrdgkwqivhfhr
sga