PDB entry 5ia1

View 5ia1 on RCSB PDB site
Description: Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with MLN8054
Class: transferase
Keywords: transferase, tyrosine-protein kinase, receptor, ATP-binding
Deposited on 2016-02-21, released 2016-11-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-12-28, with a file datestamp of 2016-12-22.
Experiment type: XRAY
Resolution: 2.04 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ephrin type-A receptor 2
    Species: Homo sapiens [TaxId:9606]
    Gene: EPHA2, ECK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5ia1a_
  • Heterogens: ZZL, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5ia1A (A:)
    gdpnqavlkftteihpscvtrqkvigagefgevykgmlktssgkkevpvaiktlkagyte
    kqrvdflgeagimgqfshhniirlegviskykpmmiiteymengaldkflrekdgefsvl
    qlvgmlrgiaagmkylanmnyvhrdlaarnilvnsnlvckvsdfglsrvleddpeatytt
    sggkipirwtapeaisyrkftsasdvwsfgivmwevmtygerpywelsnhevmkaindgf
    rlptpmdcpsaiyqlmmqcwqqerarrpkfadivsildklirapdslktladfdprvsir
    lpstsg
    

    Sequence, based on observed residues (ATOM records): (download)
    >5ia1A (A:)
    tteihpscvtrqkvigagefgevykgmlkevpvaiktlkagytekqrvdflgeagimgqf
    shhniirlegviskykpmmiiteymengaldkflrekdgefsvlqlvgmlrgiaagmkyl
    anmnyvhrdlaarnilvnsnlvckvsdfglsipirwtapeaisyrkftsasdvwsfgivm
    wevmtygerpywelsnhevmkaindgfrlptpmdcpsaiyqlmmqcwqqerarrpkfadi
    vsildklirapdslktladfd