PDB entry 5i5v

View 5i5v on RCSB PDB site
Description: x-ray crystal structure at 1.94a resolution of human mitochondrial branched chain aminotransferase (bcatm) complexed with a thienopyrimidine compound and an internal aldimine linked plp cofactor.
Class: transferase
Keywords: fold type IV, transferase
Deposited on 2016-02-15, released 2016-03-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-04-06, with a file datestamp of 2016-04-01.
Experiment type: XRAY
Resolution: 1.94 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Branched-chain-amino-acid aminotransferase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: BCAT2, BCATM, BCT2, ECA40
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5i5va_
  • Chain 'B':
    Compound: Branched-chain-amino-acid aminotransferase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: BCAT2, BCATM, BCT2, ECA40
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5i5vb_
  • Heterogens: PLP, 68A, CL, EDO, DMS, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5i5vA (A:)
gshmasssfkaadlqlemtqkphkkpgpgeplvfgktftdhmlmvewndkgwgqpriqpf
qnltlhpassslhyslqlfegmkafkgkdqqvrlfrpwlnmdrmlrsamrlclpsfdkle
llecirrlievdkdwvpdaagtslyvrpvlignepslgvsqptrallfvilcpvgayfpg
gsvtpvslladpafirawvggvgnyklggnygptvlvqqealkrgceqvlwlygpdhqlt
evgtmnifvywthedgvlelvtpplngvilpgvvrqslldmaqtwgefrvvertitmkql
lraleegrvrevfgsgtacqvcpvhrilykdrnlhiptmengpelilrfqkelkeiqygi
rahewmfpv

    Sequence, based on observed residues (ATOM records): (download) 
    >5i5vA (A:)
ssfkaadlqlemtqkphkkpgplvfgktftdhmlmvewndkgwgqpriqpfqnltlhpas
sslhyslqlfegmkafkgkdqqvrlfrpwlnmdrmlrsamrlclpsfdklellecirrli
evdkdwvpdaagtslyvrpvlignepslgvsqptrallfvilcpvgayfpggsvtpvsll
adpafirawvggvgnyklggnygptvlvqqealkrgceqvlwlygpdhqltevgtmnifv
ywthedgvlelvtpplngvilpgvvrqslldmaqtwgefrvvertitmkqllraleegrv
revfgsgtacqvcpvhrilykdrnlhiptmengpelilrfqkelkeiqygirahewmfpv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5i5vB (B:)
gshmasssfkaadlqlemtqkphkkpgpgeplvfgktftdhmlmvewndkgwgqpriqpf
qnltlhpassslhyslqlfegmkafkgkdqqvrlfrpwlnmdrmlrsamrlclpsfdkle
llecirrlievdkdwvpdaagtslyvrpvlignepslgvsqptrallfvilcpvgayfpg
gsvtpvslladpafirawvggvgnyklggnygptvlvqqealkrgceqvlwlygpdhqlt
evgtmnifvywthedgvlelvtpplngvilpgvvrqslldmaqtwgefrvvertitmkql
lraleegrvrevfgsgtacqvcpvhrilykdrnlhiptmengpelilrfqkelkeiqygi
rahewmfpv

    Sequence, based on observed residues (ATOM records): (download) 
    >5i5vB (B:)
ssfkaadlqlemtqkphkkpgplvfgktftdhmlmvewndkgwgqpriqpfqnltlhpas
sslhyslqlfegmkafkgkdqqvrlfrpwlnmdrmlrsamrlclpsfdklellecirrli
evdkdwvpdaagtslyvrpvlignepslgvsqptrallfvilcpvgayfpggsvtpvsll
adpafirawvggvgnyklggnygptvlvqqealkrgceqvlwlygpdhqltevgtmnifv
ywthedgvlelvtpplngvilpgvvrqslldmaqtwgefrvvertitmkqllraleegrv
revfgsgtacqvcpvhrilykdrnlhiptmengpelilrfqkelkeiqygirahewmfpv