PDB entry 5i2j

View 5i2j on RCSB PDB site
Description: Structure of the human GluN1/GluN2A LBD in complex with GNE0723
Class: transport protein
Keywords: NMDA, receptor, glutamate, channel, TRANSPORT PROTEIN
Deposited on 2016-02-09, released 2016-03-16
Made obsolete by 5kdt on 2016-07-13

The last revision prior to the SCOPe 2.06 freeze date was dated 2016-04-06, with a file datestamp of 2016-04-01.
Experiment type: XRAY
Resolution: 2.44 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamate receptor ionotropic, NMDA 2A
    Species: Homo sapiens [TaxId:9606]
    Gene: GRIN2A, NMDAR2A
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q12879 (Start-140)
      • linker (141-142)
    • Uniprot Q12879 (143-End)
    Domains in SCOPe 2.06: d5i2ja_
  • Chain 'B':
    Compound: Glutamate receptor ionotropic, NMDA 1
    Species: Homo sapiens [TaxId:9606]
    Gene: Grin1, Nmdar1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q05586 (2-152)
      • linker (153-154)
    • Uniprot Q05586 (155-End)
    Domains in SCOPe 2.06: d5i2jb_
  • Heterogens: ACT, GLU, 67G, GLY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5i2jA (A:)
gspddnhlsivtleeapfvivedidpltetcvrntvpcrkfvkinnstnegmnvkkcckg
fcidilkklsrtvkftydlylvtngkhgkkvnnvwngmigevvyqravmavgsltineer
sevvdfsvpfvetgisvmvsrgtqvtglsdkkfqrphdysppfrfgtvpngsternirnn
ypymhqymtkfnqkgvedalvslktgkldafiydaavlnykagrdegcklvtigsgyifa
ttgygialqkgspwkrqidlallqfvgdgemeeletlwltgichn

    Sequence, based on observed residues (ATOM records): (download) 
    >5i2jA (A:)
dnhlsivtleeapfvivedidpetcvrntvpcrkfvkinnstnegmnvkkcckgfcidil
kklsrtvkftydlylvtngkhgkkvnnvwngmigevvyqravmavgsltineersevvdf
svpfvetgisvmvsrgtqvtglsdkkfqrphdysppfrfgtvpngsternirnnypymhq
ymtkfnqkgvedalvslktgkldafiydaavlnykagrdegcklvtigsgyifattgygi
alqkgspwkrqidlallqfvgdgemeeletlwltgich

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5i2jB (B:)
gsmstrlkivtihqepfvyvkptlsdgtckeeftvngdpvkkvictgpndtspgsprhtv
pqccygfcidlliklartmnftyevhlvadgkfgtqervnnsnkkewngmmgellsgqad
mivapltinneraqyiefskpfkyqgltilvkkgtritgindprlrnpsdkfiyatvkqs
svdiyfrrqvelstmyrhmekhnyesaaeaiqavrdnklhafiwdsavlefeasqkcdlv
ttgelffrsgfgigmrkdspwkqnvslsilkshengfmedldktwvryqecds

    Sequence, based on observed residues (ATOM records): (download) 
    >5i2jB (B:)
mstrlkivtihqepfvyvkptlsdgtckeeftvngdpvkkvictgpndtspgsprhtvpq
ccygfcidlliklartmnftyevhlvadgkfgtqervnkkewngmmgellsgqadmivap
ltinneraqyiefskpfkyqgltilvkkgtritgindprlrnpsdkfiyatvkqssvdiy
frrqvelstmyrhmekhnyesaaeaiqavrdnklhafiwdsavlefeasqkcdlvttgel
ffrsgfgigmrkdspwkqnvslsilkshengfmedldktwvryq