PDB entry 5hwm

View 5hwm on RCSB PDB site
Description: Crystal structure of keto-deoxy-D-galactarate dehydratase complexed with 2-oxoadipic acid
Class: lyase
Keywords: decarboxylating, dehydratase, TIM-barrel, LYASE
Deposited on 2016-01-29, released 2016-03-23
The last revision prior to the SCOPe 2.06 freeze date was dated 2016-03-23, with a file datestamp of 2016-03-18.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Probable 5-dehydro-4-deoxyglucarate dehydratase
    Species: Agrobacterium fabrum (strain C58 / ATCC 33970) [TaxId:176299]
    Gene: Atu3140, AGR_L_3338
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8UB77 (0-302)
      • conflict (1)
      • expression tag (303)
    Domains in SCOPe 2.06: d5hwma1, d5hwma2
  • Chain 'B':
    Compound: Probable 5-dehydro-4-deoxyglucarate dehydratase
    Species: Agrobacterium fabrum (strain C58 / ATCC 33970) [TaxId:176299]
    Gene: Atu3140, AGR_L_3338
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8UB77 (0-302)
      • conflict (1)
    Domains in SCOPe 2.06: d5hwmb_
  • Chain 'C':
    Compound: Probable 5-dehydro-4-deoxyglucarate dehydratase
    Species: Agrobacterium fabrum (strain C58 / ATCC 33970) [TaxId:176299]
    Gene: Atu3140, AGR_L_3338
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8UB77 (0-End)
      • conflict (1)
    Domains in SCOPe 2.06: d5hwmc_
  • Chain 'D':
    Compound: Probable 5-dehydro-4-deoxyglucarate dehydratase
    Species: Agrobacterium fabrum (strain C58 / ATCC 33970) [TaxId:176299]
    Gene: Atu3140, AGR_L_3338
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8UB77 (0-302)
      • conflict (1)
    Domains in SCOPe 2.06: d5hwmd_
  • Heterogens: OOG, FMT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5hwmA (A:)
mdpeqiktalgsgllsfpvthfdaegrfaadsyrehvewlagykapvlfaaggtgeffsl
kpdeiptivaaakevagetaivsgcgygteiavdiarsvekvgadgilllphylidapqe
glyahikkvcqsvgigvmvynrdnsvlqadtlarlcdecpnlvgfkdgtgdiglvrqita
kmgdrlmylggmptaelfaeaylgagfttyssavfnfvpglanefyaalrageratceri
lvdffypfmairnrakgyavsavkagvrlqgfnagpvraplkdltneeigmlealigthk
rkawshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >5hwmA (A:)
mdpeqiktalgsgllsfpvthfdaegrfaadsyrehvewlagykapvlfaaggtgeffsl
kpdeiptivaaakevagetaivsgcgygteiavdiarsvekvgadgilllphylidapqe
glyahikkvcqsvgigvmvynrdnsvlqadtlarlcdecpnlvgfkdgtgdiglvrqita
kmgdrlmylggmptaelfaeaylgagfttyssavfnfvpglanefyaalrageratceri
lvdffypfmairnrakgyavsavkagvrlqgfnagpvraplkdltneeigmlealigthk
rkaw

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5hwmB (B:)
mdpeqiktalgsgllsfpvthfdaegrfaadsyrehvewlagykapvlfaaggtgeffsl
kpdeiptivaaakevagetaivsgcgygteiavdiarsvekvgadgilllphylidapqe
glyahikkvcqsvgigvmvynrdnsvlqadtlarlcdecpnlvgfkdgtgdiglvrqita
kmgdrlmylggmptaelfaeaylgagfttyssavfnfvpglanefyaalrageratceri
lvdffypfmairnrakgyavsavkagvrlqgfnagpvraplkdltneeigmlealigthk
rkawshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >5hwmB (B:)
mdpeqiktalgsgllsfpvthfdaegrfaadsyrehvewlagykapvlfaaggtgeffsl
kpdeiptivaaakevagetaivsgcgygteiavdiarsvekvgadgilllphylidapqe
glyahikkvcqsvgigvmvynrdnsvlqadtlarlcdecpnlvgfkdgtgdiglvrqita
kmgdrlmylggmptaelfaeaylgagfttyssavfnfvpglanefyaalrageratceri
lvdffypfmairnrakgyavsavkagvrlqgfnagpvraplkdltneeigmlealigthk
rka

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5hwmC (C:)
mdpeqiktalgsgllsfpvthfdaegrfaadsyrehvewlagykapvlfaaggtgeffsl
kpdeiptivaaakevagetaivsgcgygteiavdiarsvekvgadgilllphylidapqe
glyahikkvcqsvgigvmvynrdnsvlqadtlarlcdecpnlvgfkdgtgdiglvrqita
kmgdrlmylggmptaelfaeaylgagfttyssavfnfvpglanefyaalrageratceri
lvdffypfmairnrakgyavsavkagvrlqgfnagpvraplkdltneeigmlealigthk
rkawshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >5hwmC (C:)
mdpeqiktalgsgllsfpvthfdaegrfaadsyrehvewlagykapvlfaaggtgeffsl
kpdeiptivaaakevagetaivsgcgygteiavdiarsvekvgadgilllphylidapqe
glyahikkvcqsvgigvmvynrdnsvlqadtlarlcdecpnlvgfkdgtgdiglvrqita
kmgdrlmylggmptaelfaeaylgagfttyssavfnfvpglanefyaalrageratceri
lvdffypfmairnrakgyavsavkagvrlqgfnagpvraplkdltneeigmlealigthk
r

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5hwmD (D:)
mdpeqiktalgsgllsfpvthfdaegrfaadsyrehvewlagykapvlfaaggtgeffsl
kpdeiptivaaakevagetaivsgcgygteiavdiarsvekvgadgilllphylidapqe
glyahikkvcqsvgigvmvynrdnsvlqadtlarlcdecpnlvgfkdgtgdiglvrqita
kmgdrlmylggmptaelfaeaylgagfttyssavfnfvpglanefyaalrageratceri
lvdffypfmairnrakgyavsavkagvrlqgfnagpvraplkdltneeigmlealigthk
rkawshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >5hwmD (D:)
mdpeqiktalgsgllsfpvthfdaegrfaadsyrehvewlagykapvlfaaggtgeffsl
kpdeiptivaaakevagetaivsgcgygteiavdiarsvekvgadgilllphylidapqe
glyahikkvcqsvgigvmvynrdnsvlqadtlarlcdecpnlvgfkdgtgdiglvrqita
kmgdrlmylggmptaelfaeaylgagfttyssavfnfvpglanefyaalrageratceri
lvdffypfmairnrakgyavsavkagvrlqgfnagpvraplkdltneeigmlealigthk
rka