PDB entry 5hvt

View 5hvt on RCSB PDB site
Description: Crystal Structure of Macrophage Migration Inhibitory Factor (MIF) with a Potent Inhibitor (NVS-2)
Class: ISOMERASE/ISOMERASE inhibitor
Keywords: Cytokine, Inhibitor, Complex, ISOMERASE-ISOMERASE inhibitor complex
Deposited on 2016-01-28, released 2016-06-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-07-20, with a file datestamp of 2016-07-15.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: macrophage migration inhibitory factor
  Species: Homo sapiens [TaxId:9606]
  Gene: MIF, GLIF, MMIF
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14174 (0-113)
  Domains in SCOPe 2.08: d5hvta_
• Chain 'B':
  Compound: macrophage migration inhibitory factor
  Species: Homo sapiens [TaxId:9606]
  Gene: MIF, GLIF, MMIF
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14174 (0-113)
  Domains in SCOPe 2.08: d5hvtb_
• Chain 'C':
  Compound: macrophage migration inhibitory factor
  Species: Homo sapiens [TaxId:9606]
  Gene: MIF, GLIF, MMIF
  Database cross-references and differences (RAF-indexed):
  • Uniprot P14174 (0-113)
  Domains in SCOPe 2.08: d5hvtc_
• Heterogens: SO4, NVS, GOL, IPA, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >5hvtA (A:)
  pmfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
  lhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >5hvtB (B:)
  pmfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
  lhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa
  

  
  
• Chain 'C':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >5hvtC (C:)
  pmfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
  lhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa