PDB entry 5hsh

View 5hsh on RCSB PDB site
Description: Crystal structure of the G291R mutant of human phosphoglucomutase 1
Class: isomerase
Keywords: phosphoglucomutase, isomerase, enzyme, missense mutant
Deposited on 2016-01-25, released 2016-04-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-27, with a file datestamp of 2019-11-22.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphoglucomutase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PGM1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P36871 (0-561)
      • engineered mutation (290)
    Domains in SCOPe 2.08: d5hsha1, d5hsha2, d5hsha3, d5hsha4
  • Chain 'B':
    Compound: Phosphoglucomutase-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PGM1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P36871 (0-561)
      • engineered mutation (290)
    Domains in SCOPe 2.08: d5hshb1, d5hshb2, d5hshb3, d5hshb4
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5hshA (A:)
mvkivtvktqayqdqkpgtsglrkrvkvfqssanyaenfiqsiistvepaqrqeatlvvg
gdgrfymkeaiqliariaaangigrlvigqngilstpavsciirkikaiggiiltashnp
ggpngdfgikfnisnggpapeaitdkifqisktieeyavcpdlkvdlgvlgkqqfdlenk
fkpftveivdsveayatmlrsifdfsalkellsgpnrlkiridamhgvvgpyvkkilcee
lgapansavncvpledfgghhpdpnltyaadlvetmksgehdfgaafdgdrdrnmilgkh
gffvnpsdsvaviaanifsipyfqqtgvrgfarsmptsgaldrvasatkialyetptgwk
ffgnlmdasklslcgeesfgtgsdhirekdglwavlawlsilatrkqsvedilkdhwqky
grnfftrydyeeveaegankmmkdlealmfdrsfvgkqfsandkvytvekadnfeysdpv
dgsisrnqglrliftdgsrivfrlsgtgsagatirlyidsyekdvakinqdpqvmlapli
sialkvsqlqertgrtaptvit

    Sequence, based on observed residues (ATOM records): (download) 
    >5hshA (A:)
mvkivtvktqayqdqkpgtsglrkrvkvfqssanyaenfiqsiistvepaqrqeatlvvg
gdgymkeaiqliariaaangigrlvigqngilstpavsciirkikaiggiiltadfgikf
nisnggpapeaitdkifqisktieeyavcpdlkvdlgvlgkqqfdlenkfkpftveivds
veayatmlrsifdfsalkellsgpnrlkiridamhgvvgpyvkkilceelgapansavnc
vpleyaadlvetmksgehdfgaafdgdrdrnmilgkhgffvnpsdsvaviaanifsipyf
qqtgvrgfarsmptsgaldrvasatkialyetptgwkffgnlmdasklslcgeesfgtgs
dhirekdglwavlawlsilatrkqsvedilkdhwqkygrnfftrydyeeveaegankmmk
dlealmfdrsfvgkqfsandkvytvekadnfeysdpvdgsisrnqglrliftdgsrivfr
lsagatirlyidsyekdvakinqdpqvmlaplisialkvsqlqertgrtaptvit

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5hshB (B:)
mvkivtvktqayqdqkpgtsglrkrvkvfqssanyaenfiqsiistvepaqrqeatlvvg
gdgrfymkeaiqliariaaangigrlvigqngilstpavsciirkikaiggiiltashnp
ggpngdfgikfnisnggpapeaitdkifqisktieeyavcpdlkvdlgvlgkqqfdlenk
fkpftveivdsveayatmlrsifdfsalkellsgpnrlkiridamhgvvgpyvkkilcee
lgapansavncvpledfgghhpdpnltyaadlvetmksgehdfgaafdgdrdrnmilgkh
gffvnpsdsvaviaanifsipyfqqtgvrgfarsmptsgaldrvasatkialyetptgwk
ffgnlmdasklslcgeesfgtgsdhirekdglwavlawlsilatrkqsvedilkdhwqky
grnfftrydyeeveaegankmmkdlealmfdrsfvgkqfsandkvytvekadnfeysdpv
dgsisrnqglrliftdgsrivfrlsgtgsagatirlyidsyekdvakinqdpqvmlapli
sialkvsqlqertgrtaptvit

    Sequence, based on observed residues (ATOM records): (download) 
    >5hshB (B:)
mvkivtvktqayqdqkpgtsglrkrvkvfqssanyaenfiqsiistvepaqrqeatlvvg
gdgymkeaiqliariaaangigrlvigqngilstpavsciirkikaiggiiltasdfgik
fnisnggpapeaitdkifqisktieeyavcpdlkvdlgvlgkqqfdlenkfkpftveivd
sveayatmlrsifdfsalkellsgpnrlkiridamhgvvgpyvkkilceelgapansavn
cvaadlvetmksgehdfgaafdgdrdrnmilgkhgffvnpsdsvaviaanifsipyfqqt
gvrgfarsmptsgaldrvasatkialyetptgwkffgnlmdasklslcgeesfgtgsdhi
rekdglwavlawlsilatrkqsvedilkdhwqkygrnfftrydyeeveaegankmmkdle
almfdrsfvgkqfsandkvytvekadnfeysdpvdgsisrnqglrliftdgsrivfrlti
rlyidsyekdvakinqdpqvmlaplisialkvsqlqertgrtaptvit