PDB entry 5hpy

View 5hpy on RCSB PDB site
Description: Crystal Structure of RhoA.GDP.MgF3-in complex with human Myosin 9b RhoGAP domain
Class: gene regulation/signaling protein
Keywords: Complex, Rho GTPases, RhoGAP, GENE REGULATION-SIGNALING PROTEIN complex
Deposited on 2016-01-21, released 2016-07-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-08-17, with a file datestamp of 2016-08-12.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Unconventional myosin-IXb
    Species: Homo sapiens [TaxId:9606]
    Gene: MYO9B, MYR5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5hpya_
  • Chain 'B':
    Compound: transforming protein rhoa
    Species: Homo sapiens [TaxId:9606]
    Gene: RHOA, ARH12, ARHA, RHO12
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61586 (6-End)
      • engineered mutation (28)
    Domains in SCOPe 2.07: d5hpyb_
  • Chain 'D':
    Compound: Unconventional myosin-IXb
    Species: Homo sapiens [TaxId:9606]
    Gene: MYO9B, MYR5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5hpyd_
  • Chain 'F':
    Compound: transforming protein rhoa
    Species: Homo sapiens [TaxId:9606]
    Gene: RHOA, ARH12, ARHA, RHO12
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61586 (6-End)
      • engineered mutation (28)
    Domains in SCOPe 2.07: d5hpyf_
  • Heterogens: MGF, MG, GDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5hpyA (A:)
    gpgsefpgvepghfgvcvdsltsdkasvpivlekllehvemhglyteglyrksgaanrtr
    elrqalqtdpaavklenfpihaitgvlkqwlrelpeplmtfaqygdflravelpekqeql
    aaiyavlehlpeanhnslerlifhlvkvalledvnrmspgalaiifapcllrcpdnsdpl
    tsmkdvlkittcvemlikeqmrkykvkmeeisqleaaesiafrrlsllrqna
    

    Sequence, based on observed residues (ATOM records): (download)
    >5hpyA (A:)
    ghfgvcvsvpivlekllehvemhglyteglyrksgaanrtrelrqalqtdpaavklenfp
    ihaitgvlkqwlrelpeplmtfaqygdflravelpekqeqlaaiyavlehlpeanhnsle
    rlifhlvkvalledvnrmspgalaiifapcllrcsdpltsmkdvlkittcvemlikeqmr
    kykvkmeeisql
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5hpyB (B:)
    gpgsefairkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvela
    lwdtagqedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvg
    nkkdlrndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematr
    aalqa
    

    Sequence, based on observed residues (ATOM records): (download)
    >5hpyB (B:)
    airkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdtag
    qedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlr
    ndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalq
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >5hpyD (D:)
    gpgsefpgvepghfgvcvdsltsdkasvpivlekllehvemhglyteglyrksgaanrtr
    elrqalqtdpaavklenfpihaitgvlkqwlrelpeplmtfaqygdflravelpekqeql
    aaiyavlehlpeanhnslerlifhlvkvalledvnrmspgalaiifapcllrcpdnsdpl
    tsmkdvlkittcvemlikeqmrkykvkmeeisqleaaesiafrrlsllrqna
    

    Sequence, based on observed residues (ATOM records): (download)
    >5hpyD (D:)
    fgvcsvpivlekllehvemhglyteglyrksgaanrtrelrqalqtdpaavklenfpiha
    itgvlkqwlrelpeplmtfaqygdflravelpekqeqlaaiyavlehlpeanhnslerli
    fhlvkvalledvnrmspgalaiifapcllrcpsdpltsmkdvlkittcvemlikeqmrky
    kvkmeeisql
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >5hpyF (F:)
    gpgsefairkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvela
    lwdtagqedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvg
    nkkdlrndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematr
    aalqa
    

    Sequence, based on observed residues (ATOM records): (download)
    >5hpyF (F:)
    airkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdtag
    qedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlr
    ndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalq