PDB entry 5hpk

View 5hpk on RCSB PDB site
Description: System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes: NEDD4L and UbV NL.1
Class: ligase
Keywords: HECT, E3 ligase, NEDD4L, ubiquitin, Ubv, LIGASE
Deposited on 2016-01-20, released 2016-03-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2016-04-20, with a file datestamp of 2016-04-15.
Experiment type: XRAY
Resolution: 2.43 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: E3 ubiquitin-protein ligase NEDD4-like
    Species: Homo sapiens [TaxId:9606]
    Gene: NEDD4L, KIAA0439, NEDL3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96PU5 (1-End)
      • expression tag (0)
    Domains in SCOPe 2.08: d5hpka1, d5hpka2
  • Chain 'B':
    Compound: Ubiquitin variant NL.1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5HPK
    Domains in SCOPe 2.08: d5hpkb1, d5hpkb2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5hpkA (A:)
gsrefkqkydyfrkklkkpadipnrfemklhrnnifeesyrrimsvkrpdvlkarlwief
esekgldyggvarewffllskemfnpyyglfeysatdnytlqinpnsglcnedhlsyftf
igrvaglavfhgklldgffirpfykmmlgkqitlndmesvdseyynslkwilendpteld
lmfcideenfgqtyqvdlkpngseimvtnenkreyidlviqwrfvnrvqkqmnaflegft
ellpidlikifdenelellmcglgdvdvndwrqhsiykngycpnhpviqwfwkavllmda
ekrirllqfvtgtsrvpmngfaelygsngpqlftieqwgspeklprahtcfnrldlppye
tfedlrekllmavenaqgfegvd

    Sequence, based on observed residues (ATOM records): (download) 
    >5hpkA (A:)
gsrefkqkydyfrkklkkpadipnrfemklhrnnifeesyrrimsvkrpdvlkarlwief
edyggvarewffllskemfnpyyglfeysatdnytlqinpnsglcnedhlsyftfigrva
glavfhgklldgffirpfykmmlgkqitlndmesvdseyynslkwilendpteldlmfci
deenfgqtyqvdlkpngseimvtnenkreyidlviqwrfvnrvqkqmnaflegftellpi
dlikifdenelellmcglgdvdvndwrqhsiykngycpnhpviqwfwkavllmdaekrir
llqfvtgtsrvpmngfaelygsngpqlftieqwgspeklprahtcfnrldlppyetfedl
rekllmavenaq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5hpkB (B:)
mghhhhhhmrifvrtptrktitlevepsdtienvkakiqdkegippdqqvlifagnrled
grtlsdynipkestlylfmrlrglen

    Sequence, based on observed residues (ATOM records): (download) 
    >5hpkB (B:)
hmrifvrtptrktitlevepsdtienvkakiqdkegippdqqvlifagnrledgrtlsdy
nipkestlylfmrlrgle