PDB entry 5hi6

View 5hi6 on RCSB PDB site
Description: The high resolution structure of dihydrofolate reductase from Yersinia pestis complex with methotrexate as closed form
Class: oxidoreductase
Keywords: Structural Genomics, Center For Structural Genomics Of Infectious Diseases, CSGID, Dihydrofolate Reductase, Yersinia pestis, OXIDOREDUCTASE
Deposited on 2016-01-11, released 2016-02-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydrofolate reductase
    Species: Yersinia pestis CO92 [TaxId:214092]
    Gene: folA, AK38_2080
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5hi6a1, d5hi6a2
  • Chain 'B':
    Compound: dihydrofolate reductase
    Species: Yersinia pestis CO92 [TaxId:214092]
    Gene: folA, AK38_2080
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5hi6b1, d5hi6b2
  • Heterogens: MTX, CA, K, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5hi6A (A:)
snamiisliaalaadrvigmenampwhlpadlawfkrntlnkpvimgrktfesigrplpg
rlnivissqpgtdervtwaasieealafagnaeevmvmgggrvykqfldranrmylthid
aevggdthfpdyepdewesvfsefhdadeanshsycfeilerr

    Sequence, based on observed residues (ATOM records): (download) 
    >5hi6A (A:)
amiisliaalaadrvigmenampwhlpadlawfkrntlnkpvimgrktfesigrplpgrl
nivissqpgtdervtwaasieealafagnaeevmvmgggrvykqfldranrmylthidae
vggdthfpdyepdewesvfsefhdadeanshsycfeilerr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5hi6B (B:)
snamiisliaalaadrvigmenampwhlpadlawfkrntlnkpvimgrktfesigrplpg
rlnivissqpgtdervtwaasieealafagnaeevmvmgggrvykqfldranrmylthid
aevggdthfpdyepdewesvfsefhdadeanshsycfeilerr

    Sequence, based on observed residues (ATOM records): (download) 
    >5hi6B (B:)
namiisliaalaadrvigmenampwhlpadlawfkrntlnkpvimgrktfesigrplpgr
lnivissqpgtdervtwaasieealafagnaeevmvmgggrvykqfldranrmylthida
evggdthfpdyepdewesvfsefhdadeanshsycfeilerr