PDB entry 5hhy

View 5hhy on RCSB PDB site
Description: Structure of human Alanine:Glyoxylate Aminotransferase major allele (AGT-Ma) showing X-Ray induced reduction of PLP internal aldimine to 4'-deoxy-piridoxine-phosphate (PLR)
Class: transferase
Keywords: AMINOTRANSFERASE, DETOXIFICATION, LIVER, transferase
Deposited on 2016-01-11, released 2017-01-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-09-27, with a file datestamp of 2017-09-22.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine--pyruvate aminotransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: AGXT, AGT1, SPAT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5hhya_
  • Chain 'B':
    Compound: Serine--pyruvate aminotransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: AGXT, AGT1, SPAT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5hhyb_
  • Heterogens: PLR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5hhyA (A:)
llvtppkallkplsipnqlllgpgpsnlpprimaagglqmigsmskdmyqimdeikegiq
yvfqtrnpltlvisgsghcaleaalvnvlepgdsflvgangiwgqravdigerigarvhp
mtkdpgghytlqeveeglaqhkpvllflthgesstgvlqpldgfgelchrykclllvdsv
aslggtplymdrqgidilysgsqkalnappgtslisfsdkakkkmysrktkpfsfyldik
wlanfwgcddqprmyhhtipvislyslreslaliaeqglenswrqhreaaaylhgrlqal
glqlfvkdpalrlptvttvavpagydwrdivsyvidhfdieimgglgpstgkvlrigllg
cnatrenvdrvtealraalqhcpkkk

    Sequence, based on observed residues (ATOM records): (download) 
    >5hhyA (A:)
llvtppkallkplsipnqlllgpgpsnlpprimaagglqmigsmskdmyqimdeikegiq
yvfqtrnpltlvisgsghcaleaalvnvlepgdsflvgangiwgqravdigerigarvhp
mtkdpgghytlqeveeglaqhkpvllflthgesstgvlqpldgfgelchrykclllvdsv
aslggtplymdrqgidilysgsqkalnappgtslisfsdkakkkmysrktkpfsfyldik
wlanfwgcddqprmyhhtipvislyslreslaliaeqglenswrqhreaaaylhgrlqal
glqlfvkdpalrlptvttvavpagydwrdivsyvidhfdieimgglgpstgkvlrigllg
cnatrenvdrvtealraalqhcpkk

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5hhyB (B:)
llvtppkallkplsipnqlllgpgpsnlpprimaagglqmigsmskdmyqimdeikegiq
yvfqtrnpltlvisgsghcaleaalvnvlepgdsflvgangiwgqravdigerigarvhp
mtkdpgghytlqeveeglaqhkpvllflthgesstgvlqpldgfgelchrykclllvdsv
aslggtplymdrqgidilysgsqkalnappgtslisfsdkakkkmysrktkpfsfyldik
wlanfwgcddqprmyhhtipvislyslreslaliaeqglenswrqhreaaaylhgrlqal
glqlfvkdpalrlptvttvavpagydwrdivsyvidhfdieimgglgpstgkvlrigllg
cnatrenvdrvtealraalqhcpkkk