PDB entry 5hex

View 5hex on RCSB PDB site
Description: Crystal Structure of Human Hexokinase 2 with cmpd 30, a 2-amino-6-benzenesulfonamide glucosamine
Class: transferase/transferase inhibitor
Keywords: inhibitor complex, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2016-01-06, released 2016-03-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.73 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5hexA (A:)
mgsshhhhhhssglenlyfqgsdqvqkvdqylyhmrlsdetlleiskrfrkemekglgat
thptaavkmlptfvrstpdgtehgeflaldlggtnfrvlwvkvtdnglqkvemenqiyai
pedimrgsgtqlfdhiaeclanfmdklqikdkklplgftfsfpchqtkldesflvswtkg
fkssgvegrdvvalirkaiqrrgdfdidivavvndtvgtmmtcgyddhnceiglivgtgs
nacymeemrhidmvegdegrmcinmewgafgddgslndirtefdqeidmgslnpgkqlfe
kmisgmymgelvrlilvkmakeellfggklspellntgrfetkdisdiegekdgirkare
vlmrlgldptqedcvathricqivstrsaslcaatlaavlqrikenkgeerlrstigvdg
svykkhphfakrlhktvrrlvpgcdvrflrsedgsgkgaamvtavayrladqhrarqktl
ehlqlshdqllevkrrmkvemerglskethasapvkmlptyvcatpdgtekgdflaldlg
gtnfrvllvrvrngkwggvemhnkiyaipqevmhgtgdelfdhivqciadfleymgmkgv
slplgftfsfpcqqnsldesillkwtkgfkasgcegedvvtllkeaihrreefdldvvav
vndtvgtmmtcgfedphcevglivgtgsnacymeemrnvelvegeegrmcvnmewgafgd
ngclddfrtefdvavdelslnpgkqrfekmisgmylgeivrnilidftkrgllfrgrise
rlktrgifetkflsqiesdclallqvrailqhlglestcddsiivkevctvvarraaqlc
gagmaavvdrirenrgldalkvtvgvdgtlyklhphfakvmhetvkdlapkcdvsflqse
dgsgkgaalitavacrireagqr

    Sequence, based on observed residues (ATOM records): (download) 
    >5hexA (A:)
dqvqkvdqylyhmrlsdetlleiskrfrkemekglgatthptaavkmlptfvrstpdgte
hgeflaldlggtnfrvlwvkvtdnglqkvemenqiyaipedisgtqlfdhiaeclanfmd
klqikdkklplgftfsfpchqtkldesflvgrdvvalirkaiqrrgdfdidivavvndtv
gtmmtcgyddhnceiglivgtgsnacymeemrhidmvegdegrmcinmewgafgddgsln
dirtefdqeidmgslnpgkqlfekmisgmymgelvrlilvkmakeellfggklspellnt
grfetkdisdiegekdgirkarevlmrlgldptqedcvathricqivstrsaslcaatla
avlqrikenkgeerlrstigvdgsvykkhphfakrlhktvrrlvpgcdvrflrsedgsgk
gaamvtavayrladqhrarqktlehlqlshdqllevkrrmkvemerglskethasapvkm
lptyvcatpdgtekgdflaldlggtnfrvllvrvrngkwggvemhnkiyaipqevmhgtg
delfdhivqciadfleymgmkgvslplgftfsfpcqqnsldesillkwtkgfkasgcege
dvvtllkeaihrreefdldvvavvndtvgtmmtcgfedphcevglivgtgsnacymeemr
nvelvegeegrmcvnmewgafgdngclddfrtefdvavdelslnpgkqrfekmisgmylg
eivrnilidftkrgllfrgriserlktrgifetkflsqiesdclallqvrailqhlgles
tcddsiivkevctvvarraaqlcgagmaavvdrirenrgldalkvtvgvdgtlyklhphf
akvmhetvkdlapkcdvsflqsedgsgkgaalitavacri

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5hexB (B:)
mgsshhhhhhssglenlyfqgsdqvqkvdqylyhmrlsdetlleiskrfrkemekglgat
thptaavkmlptfvrstpdgtehgeflaldlggtnfrvlwvkvtdnglqkvemenqiyai
pedimrgsgtqlfdhiaeclanfmdklqikdkklplgftfsfpchqtkldesflvswtkg
fkssgvegrdvvalirkaiqrrgdfdidivavvndtvgtmmtcgyddhnceiglivgtgs
nacymeemrhidmvegdegrmcinmewgafgddgslndirtefdqeidmgslnpgkqlfe
kmisgmymgelvrlilvkmakeellfggklspellntgrfetkdisdiegekdgirkare
vlmrlgldptqedcvathricqivstrsaslcaatlaavlqrikenkgeerlrstigvdg
svykkhphfakrlhktvrrlvpgcdvrflrsedgsgkgaamvtavayrladqhrarqktl
ehlqlshdqllevkrrmkvemerglskethasapvkmlptyvcatpdgtekgdflaldlg
gtnfrvllvrvrngkwggvemhnkiyaipqevmhgtgdelfdhivqciadfleymgmkgv
slplgftfsfpcqqnsldesillkwtkgfkasgcegedvvtllkeaihrreefdldvvav
vndtvgtmmtcgfedphcevglivgtgsnacymeemrnvelvegeegrmcvnmewgafgd
ngclddfrtefdvavdelslnpgkqrfekmisgmylgeivrnilidftkrgllfrgrise
rlktrgifetkflsqiesdclallqvrailqhlglestcddsiivkevctvvarraaqlc
gagmaavvdrirenrgldalkvtvgvdgtlyklhphfakvmhetvkdlapkcdvsflqse
dgsgkgaalitavacrireagqr

    Sequence, based on observed residues (ATOM records): (download) 
    >5hexB (B:)
dqvqkvdqylyhmrlsdetlleiskrfrkemekglgatthptaavkmlptfvrstpdgte
hgeflaldlggtnfrvlwvkvtdnglqkvemenqiyaipedimrgsgtqlfdhiaeclan
fmdklqikdkklplgftfsfpchqtkldesflvsssgvegrdvvalirkaiqrrgdfdid
ivavvndtvgtmmtcgyddhnceiglivgtgsnacymeemrhidmvegdegrmcinmewg
afgddgslndirtefdqeidmgslnpgkqlfekmisgmymgelvrlilvkmakeellfgg
klspellntgrfetkdisdiegekdgirkarevlmrlgldptqedcvathricqivstrs
aslcaatlaavlqrikenkgeerlrstigvdgsvykkhphfakrlhktvrrlvpgcdvrf
lrsedgsgkgaamvtavayrladqhrarqktlehlqlshdqllevkrrmkvemerglske
thasapvkmlptyvcatpdgtekgdflaldlggtnfrvllvrvrngkwggvemhnkiyai
pqevmhgtgdelfdhivqciadfleymgmkgvslplgftfsfpcqqnsldesillkwtkg
fkasgcegedvvtllkeaihrreefdldvvavvndtvgtmmtcgfedphcevglivgtgs
nacymeemrnvelvegeegrmcvnmewgafgdngclddfrtefdvavdelslnpgkqrfe
kmisgmylgeivrnilidftkrgllfrgriserlktrgifetkflsqiesdclallqvra
ilqhlglestcddsiivkevctvvarraaqlcgagmaavvdrirenrgldalkvtvgvdg
tlyklhphfakvmhetvkdlapkcdvsflqsedgsgkgaalitavacrire