PDB entry 5hdn

View 5hdn on RCSB PDB site
Description: Crystal structure of heat shock factor1-DBD complex with ds-DNA and TtT
Class: transcription
Keywords: HSF1-DBD, TtT, TRANSCRIPTION
Deposited on 2016-01-05, released 2017-01-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-09-27, with a file datestamp of 2017-09-22.
Experiment type: XRAY
Resolution: 1.68 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Heat shock factor protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: HSF1, HSTF1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q00613 (6-End)
      • expression tag (5)
    Domains in SCOPe 2.08: d5hdna1, d5hdna2
  • Chain 'B':
    Compound: Heat shock factor protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: HSF1, HSTF1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q00613 (6-End)
      • expression tag (4-5)
    Domains in SCOPe 2.08: d5hdnb1, d5hdnb2
  • Chain 'C':
    Compound: Heat shock factor protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: HSF1, HSTF1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q00613 (6-End)
      • expression tag (3-5)
    Domains in SCOPe 2.08: d5hdnc1, d5hdnc2
  • Chain 'D':
    Compound: Heat shock factor protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: HSF1, HSTF1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q00613 (6-End)
      • expression tag (5)
    Domains in SCOPe 2.08: d5hdnd1, d5hdnd2
  • Chain 'E':
    Compound: DNA (5'-d(*gp*gp*tp*tp*cp*tp*ap*gp*ap*ap*cp*c)-3')
    Species: Homo sapiens [TaxId:9606]
  • Chain 'F':
    Compound: DNA (5'-d(*gp*gp*tp*tp*cp*tp*ap*gp*ap*ap*cp*c)-3')
    Species: Homo sapiens [TaxId:9606]
  • Chain 'G':
    Compound: DNA (5'-d(*gp*gp*tp*tp*cp*tp*ap*gp*ap*ap*cp*c)-3')
    Species: Homo sapiens [TaxId:9606]
  • Chain 'H':
    Compound: DNA (5'-d(*gp*gp*tp*tp*cp*tp*ap*gp*ap*ap*cp*c)-3')
    Species: Homo sapiens [TaxId:9606]
  • Heterogens: CIT, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5hdnA (A:)
hhhhhhvpafltklwtlvsdpdtdalicwspsgnsfhvfdqgqfakevlpkyfkhnnmas
fvrqlnmygfrkvvhieqgglvkperddtefqhpcflrgqeqllenikrkvt

    Sequence, based on observed residues (ATOM records): (download) 
    >5hdnA (A:)
hvpafltklwtlvsdpdtdalicwspsgnsfhvfdqgqfakevlpkyfkhnnmasfvrql
nmygfrkvvhievkperddtefqhpcflrgqeqllenikrk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5hdnB (B:)
hhhhhhvpafltklwtlvsdpdtdalicwspsgnsfhvfdqgqfakevlpkyfkhnnmas
fvrqlnmygfrkvvhieqgglvkperddtefqhpcflrgqeqllenikrkvt

    Sequence, based on observed residues (ATOM records): (download) 
    >5hdnB (B:)
hhvpafltklwtlvsdpdtdalicwspsgnsfhvfdqgqfakevlpkyfkhnnmasfvrq
lnmygfrkvvhieqrddtefqhpcflrgqeqllenikrk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5hdnC (C:)
hhhhhhvpafltklwtlvsdpdtdalicwspsgnsfhvfdqgqfakevlpkyfkhnnmas
fvrqlnmygfrkvvhieqgglvkperddtefqhpcflrgqeqllenikrkvt

    Sequence, based on observed residues (ATOM records): (download) 
    >5hdnC (C:)
hhhvpafltklwtlvsdpdtdalicwspsgnsfhvfdqgqfakevlpkyfkhnnmasfvr
qlnmygfrkvvhieqgglvkperddtefqhpcflrgqeqllenikrk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5hdnD (D:)
hhhhhhvpafltklwtlvsdpdtdalicwspsgnsfhvfdqgqfakevlpkyfkhnnmas
fvrqlnmygfrkvvhieqgglvkperddtefqhpcflrgqeqllenikrkvt

    Sequence, based on observed residues (ATOM records): (download) 
    >5hdnD (D:)
hvpafltklwtlvsdpdtdalicwspsgnsfhvfdqgqfakevlpkyfkhnnmasfvrql
nmygfrkvvhidtefqhpcflrgqeqllenikrk

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.