PDB entry 5h8m

View 5h8m on RCSB PDB site
Description: Crystal structure of Mycobacterium tuberculosis malate synthase C619A, G459A mutant in complex with product malate
Class: transferase/transferase inhibitor
Keywords: TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2015-12-23, released 2016-10-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-01-11, with a file datestamp of 2017-01-06.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: malate synthase g
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: glcB, Rv1837c, MTCY1A11.06
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WK17
      • engineered mutation (458)
      • engineered mutation (618)
    Domains in SCOPe 2.08: d5h8ma_
  • Heterogens: MG, LMR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5h8mA (A:)
mtdrvsvgnlriarvlydfvnnealpgtdidpdsfwagvdkvvadltpqnqallnardel
qaqidkwhrrrviepidmdayrqflteigyllpepddftittsgvdaeitttagpqlvvp
vlnarfalnaanarwgslydalygtdvipetdgaekgptynkvrgdkviayarkflddsv
plssgsfgdatgftvqdgqlvvalpdkstglanpgqfagytgaaesptsvllinhglhie
ilidpesqvgttdragvkdvilesaittimdfedsvaavdaadkvlgyrnwlglnkgdla
aavdkdgtaflrvlnrdrnytapgggqftlpgrslmfvrnvghlmtndaivdtdgsevfe
gimdalftgliaihglkasdvngplinsrtgsiyivkpkmhgpaevaftcelfsrvedvl
glpqntmkigimdeerrttvnlkacikaaadrvvfintafldrtgdeihtsmeagpmvrk
gtmksqpwilayedhnvdaglaagfsgraqvgkgmwtmtelmadmvetkiaqpragasta
wvpsptaatlhalhyhqvdvaavqqglagkrratieqlltiplakelawapdeireevdn
ncqsilgyvvrwvdqgvgaskvpdihdvalmedratlrissqllanwlrhgvitsadvra
slermaplvdrqnagdvayrpmapnfddsiaflaaqelilsgaqqpngytepilhrrrre
fkaraaekpapsdragddaar

    Sequence, based on observed residues (ATOM records): (download) 
    >5h8mA (A:)
tdrvsvgnlriarvlydfvnnealpgtdidpdsfwagvdkvvadltpqnqallnardelq
aqidkwhrrridmdayrqflteigyllpepddftittsgvdaeitttagpqlvvpvlnar
falnaanarwgslydalygtdvipetdgaekgptynkvrgdkviayarkflddsvplssg
sfgdatgftvqdgqlvvalpdkstglanpgqfagytgaaesptsvllinhglhieilidp
esqvgttdragvkdvilesaittimdfedsvaavdaadkvlgyrnwlglnkgdlaarvln
rdrnytapgggqftlpgrslmfvrnvghlmtndaivdtdgsevfegimdalftgliaihg
lkasngplinsrtgsiyivkpkmhgpaevaftcelfsrvedvlglpqntmkigimdeerr
ttvnlkacikaaadrvvfintafldrtgdeihtsmeagpmvrkgtmksqpwilayedhnv
daglaagfsgraqvgkgmwtmtelmadmvetkiaqpragastawvpsptaatlhalhyhq
vdvaavqqglagkrratieqlltiplakelawapdeireevdnncqsilgyvvrwvdqgv
gaskvpdihdvalmedratlrissqllanwlrhgvitsadvraslermaplvdrqnvayr
pmapnfddsiaflaaqelilsgaqqpngytepilhrrrrefkaraa