PDB entry 5h4j

View 5h4j on RCSB PDB site
Description: Crystal structure of Human dUTPase in complex with N-[(1R)-1-[3-(Cyclopentyloxy)-phenyl]-ethyl]-3-[(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)methoxy]-1-propanesulfonamide
Class: hydrolase/hydrolase inhibitor
Keywords: Hydrolase, Hydrolase inhibitor, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2016-11-01, released 2017-11-01
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: dut
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5h4ja_
  • Heterogens: FKM, ZN, IMD, DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5h4jA (A:)
    mpcseetpaispskrarpaevggmqlrfarlsehataptrgsaraagydlysaydytipp
    mekavvktdiqialpsgcygrvaprsglaakhfidvgagvidedyrgnvgvvlfnfgkek
    fevkkgdriaqlicerifypeieevqalddtergsggfgstgkn
    

    Sequence, based on observed residues (ATOM records): (download)
    >5h4jA (A:)
    mqlrfarlsehataptrgsaraagydlysaydytippmekavvktdiqialpsgcygrva
    prsglaakhfidvgagvidedyrgnvgvvlfnfgkekfevkkgdriaqlicerifypeie
    evqald