PDB entry 5h3a

View 5h3a on RCSB PDB site
Description: Structural analysis of KSHV thymidylate synthase
Class: transferase
Keywords: thymidylate synthase, inhibitor, raltitrexed, dUMP, TRANSFERASE
Deposited on 2016-10-21, released 2017-01-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-01-18, with a file datestamp of 2017-01-13.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: orf70
    Species: Human herpesvirus 8 [TaxId:37296]
    Gene: ORF70
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5h3aa_
  • Chain 'B':
    Compound: orf70
    Species: Human herpesvirus 8 [TaxId:37296]
    Gene: ORF70
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5h3ab_
  • Heterogens: D16, UMP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5h3aA (A:)
pheelqylrqlreilcrgsdrldrtgigtlslfgmqaryslrdhfpllttkrvfwrgvvq
ellwflkgstdsrelsrtgvkiwdkngsreflagrglahrregdlgpvygfqwrhfgaay
vdadadytgqgfdqlsyivdliknnphdrriimcawnpadlslmalppchllcqfyvadg
elscqlyqrsgdmglgvpfniasyslltymlahvtglrpgefihtlgdahiykthieplr
lqltrtprpfprleilrsvssmeeftpddfrlvdycphptirm

    Sequence, based on observed residues (ATOM records): (download) 
    >5h3aA (A:)
pheelqylrqlreilcrgsdrldrtgigtlslfgmqaryslrdhfpllttkrvfwrgvvq
ellwflkgstdsrelsrtgvkiwdkngsreflagrglahrregdlgpvygfqwrhfgaay
vdadadytgqgfdqlsyivdliknnphdrriimcawnpadlslmalppchllcqfyvadg
elscqlyqrsgdmglgvpfniasyslltymlahvtglrpgefihtlgdahiykthieplr
lqltrtprpfprleilrsvssmeeftpddfrlvdycphpti

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5h3aB (B:)
pheelqylrqlreilcrgsdrldrtgigtlslfgmqaryslrdhfpllttkrvfwrgvvq
ellwflkgstdsrelsrtgvkiwdkngsreflagrglahrregdlgpvygfqwrhfgaay
vdadadytgqgfdqlsyivdliknnphdrriimcawnpadlslmalppchllcqfyvadg
elscqlyqrsgdmglgvpfniasyslltymlahvtglrpgefihtlgdahiykthieplr
lqltrtprpfprleilrsvssmeeftpddfrlvdycphptirm

    Sequence, based on observed residues (ATOM records): (download) 
    >5h3aB (B:)
pheelqylrqlreilcrgsdrltgigtlslfgmqaryslrdhfpllttkrvfwrgvvqel
lwflkgstdsrelsrtgvkiwdkngsreflagrglahrregdlgpvygfqwrhfgaayvd
adadytgqgfdqlsyivdliknnphdrriimcawnpadlslmalppchllcqfyvadgel
scqlyqrsgdmglgvpfniasyslltymlahvtglrpgefihtlgdahiykthieplrlq
ltrtprpfprleilrsvssmeeftpddfrlvdycphptirm