PDB entry 5gv5

View 5gv5 on RCSB PDB site
Description: Crystal structure of Candida antarctica Lipase B with active Ser105 modified with a phosphonate inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: Lipase, Inhibitor, Phosphonate, CAL-B, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2016-09-02, released 2017-09-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-13, with a file datestamp of 2017-09-08.
Experiment type: XRAY
Resolution: 2.89 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: lipase b
    Species: Pseudozyma antarctica [TaxId:84753]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5gv5a_
  • Chain 'B':
    Compound: lipase b
    Species: Pseudozyma antarctica [TaxId:84753]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5gv5b_
  • Chain 'C':
    Compound: lipase b
    Species: Pseudozyma antarctica [TaxId:84753]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5gv5c_
  • Chain 'D':
    Compound: lipase b
    Species: Pseudozyma antarctica [TaxId:84753]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5gv5d_
  • Chain 'E':
    Compound: lipase b
    Species: Pseudozyma antarctica [TaxId:84753]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5gv5e_
  • Chain 'F':
    Compound: lipase b
    Species: Pseudozyma antarctica [TaxId:84753]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5gv5f_
  • Chain 'G':
    Compound: lipase b
    Species: Pseudozyma antarctica [TaxId:84753]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5gv5g_
  • Chain 'H':
    Compound: lipase b
    Species: Pseudozyma antarctica [TaxId:84753]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5gv5h_
  • Heterogens: MSW, NAG

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5gv5A (A:)
    lpsgsdpafsqpksvldagltcqgaspssvskpillvpgtgttgpqsfdsnwiplstqlg
    ytpcwispppfmlndtqvnteymvnaitalyagsgnnklpvltwsqgglvaqwgltffps
    irskvdrlmafapdykgtvlagpldalavsapsvwqqttgsalttalrnaggltqivptt
    nlysatdeivqpqvsnspldssylfngknvqaqavcgplfvidhagsltsqfsyvvgrsa
    lrsttgqarsadygitdcnplpandltpeqkvaaaallapaaaaivagpkqncepdlmpy
    arpfavgkrtcsgivtp
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5gv5B (B:)
    lpsgsdpafsqpksvldagltcqgaspssvskpillvpgtgttgpqsfdsnwiplstqlg
    ytpcwispppfmlndtqvnteymvnaitalyagsgnnklpvltwsqgglvaqwgltffps
    irskvdrlmafapdykgtvlagpldalavsapsvwqqttgsalttalrnaggltqivptt
    nlysatdeivqpqvsnspldssylfngknvqaqavcgplfvidhagsltsqfsyvvgrsa
    lrsttgqarsadygitdcnplpandltpeqkvaaaallapaaaaivagpkqncepdlmpy
    arpfavgkrtcsgivtp
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >5gv5C (C:)
    lpsgsdpafsqpksvldagltcqgaspssvskpillvpgtgttgpqsfdsnwiplstqlg
    ytpcwispppfmlndtqvnteymvnaitalyagsgnnklpvltwsqgglvaqwgltffps
    irskvdrlmafapdykgtvlagpldalavsapsvwqqttgsalttalrnaggltqivptt
    nlysatdeivqpqvsnspldssylfngknvqaqavcgplfvidhagsltsqfsyvvgrsa
    lrsttgqarsadygitdcnplpandltpeqkvaaaallapaaaaivagpkqncepdlmpy
    arpfavgkrtcsgivtp
    

    Sequence, based on observed residues (ATOM records): (download)
    >5gv5C (C:)
    lpsgsdpafsqpksvldagltcqgaspssvskpillvpgtgttgpqsfdsnwiplstqlg
    ytpcwispppfmlndtqvnteymvnaitalyagsgnnklpvltwsqgglvaqwgltffps
    irskvdrlmafapdykgtvlagpldaavsapsvwqqttgsalttalrnaggltqivpttn
    lysatdeivqpqvsnspldssylfngknvqaqavcgplfvidhagsltsqfsyvvgrsal
    rsttgqarsadygitdcnplpandltpeqkvaaaallapaaaaivagpkqncepdlmpya
    rpfavgkrtcsgivtp
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >5gv5D (D:)
    lpsgsdpafsqpksvldagltcqgaspssvskpillvpgtgttgpqsfdsnwiplstqlg
    ytpcwispppfmlndtqvnteymvnaitalyagsgnnklpvltwsqgglvaqwgltffps
    irskvdrlmafapdykgtvlagpldalavsapsvwqqttgsalttalrnaggltqivptt
    nlysatdeivqpqvsnspldssylfngknvqaqavcgplfvidhagsltsqfsyvvgrsa
    lrsttgqarsadygitdcnplpandltpeqkvaaaallapaaaaivagpkqncepdlmpy
    arpfavgkrtcsgivtp
    

    Sequence, based on observed residues (ATOM records): (download)
    >5gv5D (D:)
    lpsgsdpafsqpksvldagltcqgaspssvskpillvpgtgttgpqsfdsnwiplstqlg
    ytpcwispppfmlndtqvnteymvnaitalyagsgnnklpvltwsqgglvaqwgltffps
    irskvdrlmafapdykgtvlasapsvwqqttgsalttalrnaggltqivpttnlysatde
    ivqpqvsnspldssylfngknvqaqavcgplfvidhagsltsqfsyvvgrsalrsttgqa
    rsadygitdcnplpandltpeqkvaaaallapaaaaivagpkqncepdlmpyarpfavgk
    rtcsgivtp
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >5gv5E (E:)
    lpsgsdpafsqpksvldagltcqgaspssvskpillvpgtgttgpqsfdsnwiplstqlg
    ytpcwispppfmlndtqvnteymvnaitalyagsgnnklpvltwsqgglvaqwgltffps
    irskvdrlmafapdykgtvlagpldalavsapsvwqqttgsalttalrnaggltqivptt
    nlysatdeivqpqvsnspldssylfngknvqaqavcgplfvidhagsltsqfsyvvgrsa
    lrsttgqarsadygitdcnplpandltpeqkvaaaallapaaaaivagpkqncepdlmpy
    arpfavgkrtcsgivtp
    

    Sequence, based on observed residues (ATOM records): (download)
    >5gv5E (E:)
    lpsgsdpafsqpksvldagltcqgaspssvskpillvpgtgttgpqsfdsnwiplstqlg
    ytpcwispppfmlndtqvnteymvnaitalyagsgnnklpvltwsqgglvaqwgltffps
    irskvdrlmafapdykgtvlagpldvsapsvwqqttgsalttalrnaggltqivpttnly
    satdeivqpqvsnspldssylfngknvqaqavcgplfvidhagsltsqfsyvvgrsalrs
    ttgqarsadygitdcnplpandltpeqkvaaaallapaaaaivagpkqncepdlmpyarp
    favgkrtcsgivtp
    

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5gv5F (F:)
    lpsgsdpafsqpksvldagltcqgaspssvskpillvpgtgttgpqsfdsnwiplstqlg
    ytpcwispppfmlndtqvnteymvnaitalyagsgnnklpvltwsqgglvaqwgltffps
    irskvdrlmafapdykgtvlagpldalavsapsvwqqttgsalttalrnaggltqivptt
    nlysatdeivqpqvsnspldssylfngknvqaqavcgplfvidhagsltsqfsyvvgrsa
    lrsttgqarsadygitdcnplpandltpeqkvaaaallapaaaaivagpkqncepdlmpy
    arpfavgkrtcsgivtp
    

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5gv5G (G:)
    lpsgsdpafsqpksvldagltcqgaspssvskpillvpgtgttgpqsfdsnwiplstqlg
    ytpcwispppfmlndtqvnteymvnaitalyagsgnnklpvltwsqgglvaqwgltffps
    irskvdrlmafapdykgtvlagpldalavsapsvwqqttgsalttalrnaggltqivptt
    nlysatdeivqpqvsnspldssylfngknvqaqavcgplfvidhagsltsqfsyvvgrsa
    lrsttgqarsadygitdcnplpandltpeqkvaaaallapaaaaivagpkqncepdlmpy
    arpfavgkrtcsgivtp
    

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5gv5H (H:)
    lpsgsdpafsqpksvldagltcqgaspssvskpillvpgtgttgpqsfdsnwiplstqlg
    ytpcwispppfmlndtqvnteymvnaitalyagsgnnklpvltwsqgglvaqwgltffps
    irskvdrlmafapdykgtvlagpldalavsapsvwqqttgsalttalrnaggltqivptt
    nlysatdeivqpqvsnspldssylfngknvqaqavcgplfvidhagsltsqfsyvvgrsa
    lrsttgqarsadygitdcnplpandltpeqkvaaaallapaaaaivagpkqncepdlmpy
    arpfavgkrtcsgivtp