PDB entry 5guv

View 5guv on RCSB PDB site
Description: The crystal structure of mouse DNMT1 (731-1602) mutant - R1279D
Class: transferase
Keywords: mutant, TRANSFERASE
Deposited on 2016-08-31, released 2017-08-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-03-13, with a file datestamp of 2019-03-08.
Experiment type: XRAY
Resolution: 3.08 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA (cytosine-5)-methyltransferase 1
    Species: Mus musculus [TaxId:10090]
    Gene: Dnmt1, Dnmt, Met1, Uim
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13864
      • engineered mutation (548)
    Domains in SCOPe 2.08: d5guva1, d5guva2, d5guva3
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5guvA (A:)
kdriswlgqpmkieenrtyyqkvsideemlevgdcvsvipddsskplylarvtalwedkn
gqmmfhahwfcagtdtvlgatsdplelflvgecenmqlsyihskvkviykapsenwameg
gtdpettlpgaedgktyffqlwynqeyarfesppktqptednkhkfclscirlaelrqke
mpkvleqieevdgrvycssitkngvvyrlgdsvylppeaftfnikvaspvkrpkkdpvne
tlypehyrkysdyikgsnldapepyrigrikeihcgkkkgkvneadiklrlykfyrpent
hrsyngsyhtdinmlywsdeeavvnfsdvqgrctveygedllesiqdysqggpdrfyfle
aynsktknfedppnharspgnkgkgkgkgkgkgkhqvsepkepeaaiklpklrtldvfsg
cgglsegfhqagisetlwaiemwdpaaqafrlnnpgttvftedcnvllklvmagevtnsl
gqrlpqkgdvemlcggppcqgfsgmnrfnsrtyskfknslvvsflsycdyyrprffllen
vrnfvsyrdsmvlkltlrclvrmgyqctfgvlqagqygvaqtrrraiilaaapgeklplf
peplhvfapracqlsvvvddkkfvsnitrlssgpfrtitvrdtmsdlpeiqngasnseip
yngeplswfqrqlrgshyqpilrdhickdmsplvaarmrhiplfpgsdwrdlpniqvrlg
dgviahklqytfhdvkngysstgalrgvcscaegkacdpesrqfstlipwclphtgnrhn
hwaglygrlewdgffsttvtnpepmgkqgrvlhpeqhrvvsvrecarsqgfpdsyrffgn
ildrhrqvgnavppplakaigleiklcllssa

    Sequence, based on observed residues (ATOM records): (download) 
    >5guvA (A:)
riswlgqpmkieenrtyyqkvsideemlevgdcvsvipddsskplylarvtalwedkngq
mmfhahwfcagtdtvlgatsdplelflvgecenmqlsyihskvkviykapsenwamegty
ffqlwynqeyarfesppktqptednkhkfclscirlaelrqkempkvleqieevdgrvyc
ssitkngvvyrlgdsvylppeaftfnikvaspvkrpkkdpvnetlypehyrkyldapepy
rigrikeihcgkkkgkvneadiklrlykfyrpenthrsyngsyhtdinmlywsdeeavvn
fsdvqgrctveygedllesiqdysqggpdrfyfleaynsktknfedppnharspiklpkl
rtldvfsgcgglsegfhqagisetlwaiemwdpaaqafrlnnpgttvftedcnvllklvm
agevtnslgqrlpqkgdvemlcggppcqgfsgmnrfnsrtyskfknslvvsflsycdyyr
prffllenvrnfvsyrdsmvlkltlrclvrmgyqctfgvlqagqygvaqtrrraiilaaa
pgeklplfpeplhvfapracqlsvvvddkkfvsnitrlssgpfrtitvrdtmsdlpeiqn
gasnseipyngeplswfqrqlrgshyqpilrdhickdmsplvaarmrhiplfpgsdwrdl
pniqvrlgdgviahklqytfhdvkngysstgalrgvcscaegkacdpesrqfstlipwcl
phtgnrhnhwaglygrlewdgffsttvtnpepmgkqgrvlhpeqhrvvsvrecarsqgfp
dsyrffgnildrhrqvgnavppplakaigleiklclls