PDB entry 5gut

View 5gut on RCSB PDB site
Description: The crystal structure of mouse DNMT1 (731-1602) mutant - N1248A
Class: transferase
Keywords: Mutant, TRANSFERASE
Deposited on 2016-08-31, released 2017-09-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-03-13, with a file datestamp of 2019-03-08.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA (cytosine-5)-methyltransferase 1
    Species: Mus musculus [TaxId:10090]
    Gene: Dnmt1, Dnmt, Met1, Uim
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13864
      • engineered mutation (517)
    Domains in SCOPe 2.08: d5guta1, d5guta2, d5guta3
  • Heterogens: SAH, ZN, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5gutA (A:)
kdriswlgqpmkieenrtyyqkvsideemlevgdcvsvipddsskplylarvtalwedkn
gqmmfhahwfcagtdtvlgatsdplelflvgecenmqlsyihskvkviykapsenwameg
gtdpettlpgaedgktyffqlwynqeyarfesppktqptednkhkfclscirlaelrqke
mpkvleqieevdgrvycssitkngvvyrlgdsvylppeaftfnikvaspvkrpkkdpvne
tlypehyrkysdyikgsnldapepyrigrikeihcgkkkgkvneadiklrlykfyrpent
hrsyngsyhtdinmlywsdeeavvnfsdvqgrctveygedllesiqdysqggpdrfyfle
aynsktknfedppnharspgnkgkgkgkgkgkgkhqvsepkepeaaiklpklrtldvfsg
cgglsegfhqagisetlwaiemwdpaaqafrlnnpgttvftedcnvllklvmagevtnsl
gqrlpqkgdvemlcggppcqgfsgmnrfnsrtyskfkaslvvsflsycdyyrprffllen
vrnfvsyrrsmvlkltlrclvrmgyqctfgvlqagqygvaqtrrraiilaaapgeklplf
peplhvfapracqlsvvvddkkfvsnitrlssgpfrtitvrdtmsdlpeiqngasnseip
yngeplswfqrqlrgshyqpilrdhickdmsplvaarmrhiplfpgsdwrdlpniqvrlg
dgviahklqytfhdvkngysstgalrgvcscaegkacdpesrqfstlipwclphtgnrhn
hwaglygrlewdgffsttvtnpepmgkqgrvlhpeqhrvvsvrecarsqgfpdsyrffgn
ildrhrqvgnavppplakaigleiklcllssa

    Sequence, based on observed residues (ATOM records): (download) 
    >5gutA (A:)
mkieenrtyyqkvsideemlevgdcvsvipddsskplylarvtalwedkngqmmfhahwf
cagtdtvlgatsdplelflvgecenmqlsyihskvkviykapsenwamegyffqlwynqe
yarfesppktqphkfclscirlaelrqkempkvleqieevdgrvycssitkngvvyrlgd
svylppeaftfnikvaspdpvnetlypehyrkydapepyrigrikeihcgkkkgkvnead
iklrlykfyrpenthrsyngsyhtdinmlywsdeeavvnfsdvqgrctveygedllesiq
dysqggpdrfyfleaynsktknfedppnharsplpklrtldvfsgcgglsegfhqagise
tlwaiemwdpaaqafrlnnpgttvftedcnvllklvmagevtnslgqrlpqkgdvemlcg
gppcqgfsgmnrfnsrtyskfkaslvvsflsycdyyrprffllenvrnfvsyrrsmvlkl
tlrclvrmgyqctfgvlqagqygvaqtrrraiilaaapgeklplfpeplhvfapracqls
vvvddkkfvsnitrlssgpfrtitvrdtmsdlpeiqngasnseipyngeplswfqrqlrg
shyqpilrdhickdmsplvaarmrhiplfpgsdwrdlpniqvrlgdgviahklqytfhdv
kngysstgalrgvcscaegkacdpesrqfstlipwclphtgnrhnhwaglygrlewdgff
sttvtnpepmgkqgrvlhpeqhrvvsvrecarsqgfpdsyrffgnildrhrqvgnavppp
lakaigleiklcll