PDB entry 5gri

View 5gri on RCSB PDB site
Description: Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+) and citrate
Class: oxidoreductase
Keywords: allosteric regulation, OXIDOREDUCTASE
Deposited on 2016-08-11, released 2017-02-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-04, with a file datestamp of 2017-09-29.
Experiment type: XRAY
Resolution: 2.31 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: IDH3A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5gria_
  • Chain 'B':
    Compound: Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: IDH3G
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5grib_
  • Heterogens: MG, CIT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5griA (A:)
tggvqtvtlipgdgigpeisaavmkifdaakapiqweernvtaiqgpggkwmipseakes
mdknkmglkgplktpiaaghpsmnlllrktfdlyanvrpcvsiegyktpytdvnivtire
ntegeysgiehvivdgvvqsiklitegaskriaefafeyarnnhrsnvtavhkanimrms
dglflqkcrevaesckdikfnemyldtvclnmvqdpsqfdvlvmpnlygdilsdlcagli
gglgvtpsgnigangvaifesvhgtapdiagkdmanptalllsavmmlrhmglfdhaari
eaacfatikdgksltkdlggnakcsdfteeicrrvkdld

    Sequence, based on observed residues (ATOM records): (download) 
    >5griA (A:)
vqtvtlipgdgigpeisaavmkifdaakapiqweernvtaiqwmipseakesmdknkmgl
kgplktpsmnlllrktfdlyanvrpcvsiegyktpytdvnivtirentegeysgiehviv
dgvvqsiklitegaskriaefafeyarnnhrsnvtavhkanimrmsdglflqkcrevaes
ckdikfnemyldtvclnmvqdpsqfdvlvmpnlygdilsdlcagligglgvtpsgnigan
gvaifesvhgtapdiagkdmanptalllsavmmlrhmglfdhaarieaacfatikdgksl
tkdlgnakcsdfteeicrrvkdl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5griB (B:)
fseqtippsakyggrhtvtmipgdgigpelmlhvksvfrhacvpvdfeevhvssnadeed
irnaimairrnrvalkgnietnhnlppshksrnnilrtsldlyanvihckslpgvvtrhk
didilivrentegeysslehesvagvveslkiitkakslriaeyafklaqesgrkkvtav
hkanimklgdglflqccrevaarypqitfenmivdnttmqlvsrpqqfdvmvmpnlygni
vnnvcaglvggpglvaganyghvyavfetatrntgksianknianptatllascmmldhl
klhsyatsirkavlasmdnenmhtpdiggqgttseaiqdvirhirvingravea

    Sequence, based on observed residues (ATOM records): (download) 
    >5griB (B:)
rhtvtmipgdgigpelmlhvksvfrhacvpvdfeevhvssnadeedirnaimairrnrva
lkgnietnhnlppshksrnnilrtsldlyanvihckslpgvvtrhkdidilivrentege
ysslehesvagvveslkiitkakslriaeyafklaqesgrkkvtavhkanimklgdglfl
qccrevaarypqitfenmivdnttmqlvsrpqqfdvmvmpnlygnivnnvcaglvggpgl
vaganyghvyavfetatrntgksianknianptatllascmmldhlklhsyatsirkavl
asmdnenmhtpdiggqgttseaiqdvirhirving