PDB entry 5gpi

View 5gpi on RCSB PDB site
Description: Crystal Structures of Unlinked NS2B-NS3 Protease from Zika Virus and Its Complex with a Reverse Peptide Inhibitor
Class: viral protein
Keywords: zika virus protease, serine protease, non-structural protein 3, viral protein
Deposited on 2016-08-02, released 2016-12-14
The last revision prior to the SCOPe 2.06 freeze date was dated 2016-12-14, with a file datestamp of 2016-12-09.
Experiment type: XRAY
Resolution: 1.58 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NS2B cofactor
    Species: Zika virus [TaxId:64320]
    Database cross-references and differences (RAF-indexed):
    • PDB 5GPI
    Domains in SCOPe 2.06: d5gpia_
  • Chain 'B':
    Compound: NS3 protease
    Species: Zika virus [TaxId:64320]
    Database cross-references and differences (RAF-indexed):
    • PDB 5GPI
    Domains in SCOPe 2.06: d5gpib_
  • Chain 'C':
    Compound: NS2B cofactor
    Species: Zika virus [TaxId:64320]
    Database cross-references and differences (RAF-indexed):
    • PDB 5GPI
    Domains in SCOPe 2.06: d5gpic_
  • Chain 'D':
    Compound: NS3 protease
    Species: Zika virus [TaxId:64320]
    Database cross-references and differences (RAF-indexed):
    • PDB 5GPI
    Domains in SCOPe 2.06: d5gpid_
  • Chain 'E':
    Compound: NS2B cofactor
    Species: Zika virus [TaxId:64320]
    Database cross-references and differences (RAF-indexed):
    • PDB 5GPI
    Domains in SCOPe 2.06: d5gpie_
  • Chain 'F':
    Compound: NS3 protease
    Species: Zika virus [TaxId:64320]
    Database cross-references and differences (RAF-indexed):
    • PDB 5GPI
    Domains in SCOPe 2.06: d5gpif_
  • Chain 'G':
    Compound: NS2B cofactor
    Species: Zika virus [TaxId:64320]
    Database cross-references and differences (RAF-indexed):
    • PDB 5GPI
    Domains in SCOPe 2.06: d5gpig_
  • Chain 'H':
    Compound: NS3 protease
    Species: Zika virus [TaxId:64320]
    Database cross-references and differences (RAF-indexed):
    • PDB 5GPI
    Domains in SCOPe 2.06: d5gpih_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5gpiA (A:)
mtgksvdmyieragditwekdaevtgnsprldvaldesgdfslveedgppmre

    Sequence, based on observed residues (ATOM records): (download) 
    >5gpiA (A:)
dmyieragditwekdaevtgnsprldvaldesgdfslv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5gpiB (B:)
gsgalwdvpapkevkkgettdgvyrvmtrrllgstqvgvgvmqegvfhtmwhvtkgaalr
sgegrldpywgdvkqdlvsycgpwkldaawdglsevqllavppgerakniqtlpgifktk
dgdigavaldypagtsgspildkcgrviglygngvvikngsyvsaitqgkreeetpve

    Sequence, based on observed residues (ATOM records): (download) 
    >5gpiB (B:)
ettdgvyrvmtrrllgstqvgvgvmqegvfhtmwhvtkgaalrsgegrldpywgdvkqdl
vsycgpwkldaawdglsevqllavppgerakniqtlpgifktkdgdigavaldypagtsg
spildkcgrviglygngvvikngsyvsaitqgkr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5gpiC (C:)
mtgksvdmyieragditwekdaevtgnsprldvaldesgdfslveedgppmre

    Sequence, based on observed residues (ATOM records): (download) 
    >5gpiC (C:)
myieragditwekdaevtgnsprldvaldesgdfslv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5gpiD (D:)
gsgalwdvpapkevkkgettdgvyrvmtrrllgstqvgvgvmqegvfhtmwhvtkgaalr
sgegrldpywgdvkqdlvsycgpwkldaawdglsevqllavppgerakniqtlpgifktk
dgdigavaldypagtsgspildkcgrviglygngvvikngsyvsaitqgkreeetpve

    Sequence, based on observed residues (ATOM records): (download) 
    >5gpiD (D:)
ttdgvyrvmtstqvgvgvmqegvfhtmwhvtkgaalrsgegrldpywgdvkqdlvsycgp
wkldaawdglsevqllavppgerakniqtlpgifktkdgdigavaldypagtsgspildk
cgrviglygngvvikngsyvsaitqgkr

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5gpiE (E:)
mtgksvdmyieragditwekdaevtgnsprldvaldesgdfslveedgppmre

    Sequence, based on observed residues (ATOM records): (download) 
    >5gpiE (E:)
dmyieragditwekdaevtgnsprldvaldesgdfslv

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >5gpiF (F:)
gsgalwdvpapkevkkgettdgvyrvmtrrllgstqvgvgvmqegvfhtmwhvtkgaalr
sgegrldpywgdvkqdlvsycgpwkldaawdglsevqllavppgerakniqtlpgifktk
dgdigavaldypagtsgspildkcgrviglygngvvikngsyvsaitqgkreeetpve

    Sequence, based on observed residues (ATOM records): (download) 
    >5gpiF (F:)
tdgvyrvmtrrllgstqvgvgvmqegvfhtmwhvtkgaalrsgegrldpywgdvkqdlvs
ycgpwkldaawdglsevqllavppgerakniqtlpgifktkdgdigavaldypagtsgsp
ildkcgrviglygngvvikngsyvsaitqgkr

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >5gpiG (G:)
mtgksvdmyieragditwekdaevtgnsprldvaldesgdfslveedgppmre

    Sequence, based on observed residues (ATOM records): (download) 
    >5gpiG (G:)
dmyieragditwekdaevtgnsprldvaldesgdfslvee

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >5gpiH (H:)
gsgalwdvpapkevkkgettdgvyrvmtrrllgstqvgvgvmqegvfhtmwhvtkgaalr
sgegrldpywgdvkqdlvsycgpwkldaawdglsevqllavppgerakniqtlpgifktk
dgdigavaldypagtsgspildkcgrviglygngvvikngsyvsaitqgkreeetpve

    Sequence, based on observed residues (ATOM records): (download) 
    >5gpiH (H:)
evkkgettdgvyrvmttqvgvgvmqegvfhtmwhvtkgaalrsgegrldpywgdvkqdlv
sycgpwkldaawdglsevqllavppgerakniqtlpgifktkdgdigavaldypagtsgs
pildkcgrviglygngvvikngsyvsaitqgkr